TR-599: Technical Report Pathology Tables and Curves
Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long Term, Genetic Toxicology Studies
https://doi.org/10.22427/NTP-DATA-TR-599
Gestational/Lactational and Litter tables were re-analyzed and updated tables posted on 5-November-2019
On 1/20/2020 duplicate E03 and E04 tables were removed from the Rat chronic study. Water consumption tables and graphs of biological sample analysis were also added for each study.
E08 tables were added on 17-April-2020
Genetox studies were added on 10-October-2020
The PA06 table and individual animal data was updated to reflect correct animal assignments on 02-Jul-2021
Gestational/Lactational and Litter tables were re-analyzed and updated tables posted on 5-November-2019
On 1/20/2020 duplicate E03 and E04 tables were removed from the Rat chronic study. Water consumption tables and graphs of biological sample analysis were also added for each study.
E08 tables were added on 17-April-2020
Genetox studies were added on 10-October-2020
The PA06 table and individual animal data was updated to reflect correct animal assignments on 02-Jul-2021
TR-599: Sodium Tungstate Dihydrate
Short-Term
3-Month with Perinatal Study Tables - Rats
- E03 - Growth Curves (72 KB)
- E04 - Mean Body Weights and Survival Table (18 KB)
- E05 - Clinical Observations Summary (14 KB)
- E07 - Mean Water Consumption by Treatment Group (15 KB)
- E08 - Water and Compound Consumption Table (23 KB)
- Gestational and Lactational Chemical Consumption (21 KB)
- Gestational Body Weights (grams) (21 KB)
- Gestational Water Consumption (grams) (18 KB)
- Lactational Body Weights (grams) (20 KB)
- Lactational Water Consumption (grams) (19 KB)
- Litter Data By Dam-PND1 (25 KB)
- Live Litter Size and Survival-PND 4 and 21 (24 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (28 KB)
- P04 - Neoplasms by Individual Animal (197 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (33 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (198 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (67 KB)
- P14 - Individual Animal Pathology Data (254 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (29 KB)
- P40 - Survival Curves (57 KB)
- PA06 - Organ_Weights_Summary (86 KB)
- PA41 - Clinical_Chemistry_Summary (239 KB)
- PA43 - Hematology_Summary (260 KB)
- PA44 - Urinalysis_Summary (329 KB)
- PA48 - Tissue_Concentration_Summary (45 KB)
- PA48C - Tissue Concentration Curve (408 KB)
- Pup Body Weights (grams) (22 KB)
- R02 - Reproductive_Performance_Summary (42 KB)
- R06 - Andrology_Summary (47 KB)
- R07 - Hormone_Summary (44 KB)
3-Month with Perinatal Individual Animal Data - Rats
- Female Individual Animal Body Weight Data (34 KB)
- Female Individual Animal Clinical Observations (4 KB)
- Female Individual Animal Non Neoplastic Pathology Data (22 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Individual Animal Andrology Data (8 KB)
- Individual Animal Clinical Chemistry Data (14 KB)
- Individual Animal DamID and PupID Data (8 KB)
- Individual Animal Hematology Data (17 KB)
- Individual Animal Hormone Data (8 KB)
- Individual Animal Organ Weight Data (12 KB)
- Individual Animal Reproductive Performance Data (7 KB)
- Individual Animal Tissue Concentration Data (9 KB)
- Individual Animal Urinalysis Data (22 KB)
- Male Individual Animal Body Weight Data (34 KB)
- Male Individual Animal Non Neoplastic Pathology Data (26 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
3-Month Study Tables - Mice
- E03 - Growth Curves (65 KB)
- E04 - Mean Body Weights and Survival Table (17 KB)
- E05 - Clinical Observations Summary (11 KB)
- E07 - Mean Water Consumption by Treatment Group (15 KB)
- E08 - Water and Compound Consumption Table (23 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (28 KB)
- P04 - Neoplasms by Individual Animal (198 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (33 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (199 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (66 KB)
- P14 - Individual Animal Pathology Data (254 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (29 KB)
- P40 - Survival Curves (57 KB)
- PA06 - Organ_Weights_Summary (86 KB)
- PA43 - Hematology_Summary (278 KB)
- PA48 - Tissue_Concentration_Summary (47 KB)
- PA48C - Tissue Concentration Curve (419 KB)
- R06 - Andrology_Summary (47 KB)
3-Month Individual Animal Data - Mice
- Female Individual Animal Body Weight Data (33 KB)
- Female Individual Animal Clinical Observations (2 KB)
- Female Individual Animal Non Neoplastic Pathology Data (12 KB)
- Female Individual Animal Survival Data (11 KB)
- Female Individual Animal Terminal Body Weight Data (18 KB)
- Individual Animal Andrology Data (8 KB)
- Individual Animal Hematology Data (17 KB)
- Individual Animal Organ Weight Data (11 KB)
- Individual Animal Tissue Concentration Data (8 KB)
- Male Individual Animal Body Weight Data (33 KB)
- Male Individual Animal Non Neoplastic Pathology Data (13 KB)
- Male Individual Animal Survival Data (11 KB)
- Male Individual Animal Terminal Body Weight Data (18 KB)
Long Term
Chronic with Perinatal Study Tables - Rats
- Analysis of PND 1 Litter Data (23 KB)
- Analysis of PND 4 Live Litter Size and Survival (23 KB)
- E01 - Animal Removal Summary By Treatment Group (12 KB)
- E02 - Animals Removed from Experiment (144 KB)
- E03 - Growth Curves (Litter based) (62 KB)
- E04 - Mean Body Weights and Survival (Litter based) (18 KB)
- E05 - Clinical Observations Summary (22 KB)
- E07 - Mean Water Consumption by Treatment Group (25 KB)
- E08 - Water and Compound Consumption Table (37 KB)
- E12 - Animal History (1 MB)
- I05 - Clinical Observations Summary (45 KB)
- Litter Data Analysis of Gestational/Lactational Chemical Consumption (19 KB)
- Litter Data Analysis of Gestational Body Weight (20 KB)
- Litter Data Analysis of Gestational Water Consumption (18 KB)
- Litter Data Analysis of Lactational Body Weight (21 KB)
- Litter Data Analysis of Lactational Water Consumption (18 KB)
- Litter Data Analysis of Pup Body Weights (22 KB)
- Litter Data Analysis of Pup Body Weights (cont'd) (14 KB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (52 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (66 KB)
- P04 - Neoplasms by Individual Animal (648 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (49 KB)
- P08 - Litter Statistical Analysis of Primary Tumors (174 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (892 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (523 KB)
- P11 - Statistical Analysis of Survival Data (21 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (580 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (68 KB)
- P40 - Survival Curves (475 KB)
- PA06 - Organ Weights Summary (229 KB)
- PA48 - Summary of Tissue Concentration (173 KB)
- PA48C - Tissue Concentration Curve (4 MB)
- R02 - Reproductive Performance Summary (38 KB)
Chronic with Perinatal Individual Animal Data - Rats
- Female Individual Animal Body Weight Data (384 KB)
- Female Individual Animal Clinical Observations (201 KB)
- Female Individual Animal Neoplastic Pathology Data (108 KB)
- Female Individual Animal Non Neoplastic Pathology Data (552 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Female Pup Individual Animal Body Weight Data (48 KB)
- Female Pup Individual Animal Body Weight Data (40 KB)
- Female Pup Individual Animal Body Weight Data (222 KB)
- Individual Animal Clinical Observations Data (10 KB)
- Individual Animal DamID and PupID Data (30 KB)
- Individual Animal Organ Weight Data (28 KB)
- Individual Animal Reproductive Performance Data (11 KB)
- Individual Animal Tissue Concentration Data (19 KB)
- Individual Animal Urinalysis Data (20 KB)
- Individual Pup Census and Litter Weight by Sex Data (25 KB)
- Male Individual Animal Body Weight Data (388 KB)
- Male Individual Animal Clinical Observations (178 KB)
- Male Individual Animal Neoplastic Pathology Data (104 KB)
- Male Individual Animal Non Neoplastic Pathology Data (778 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)
- Male Pup Individual Animal Body Weight Data (229 KB)
Chronic Study Tables - Mice
- E01 - Animal Removal Summary By Treatment Group (12 KB)
- E02 - Animals Removed from Experiment (107 KB)
- E03 - Growth Curves (459 KB)
- E04 - Mean Body Weights and Survival Table (23 KB)
- E05 - Clinical Observations Summary (19 KB)
- E07 - Mean Water Consumption by Treatment Group (24 KB)
- E08 - Water and Compound Consumption Table (35 KB)
- E12 - Animal History (1 MB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (55 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (63 KB)
- P04 - Neoplasms by Individual Animal (717 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (50 KB)
- P08 - Statistical Analysis of Primary Tumors (219 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (864 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (551 KB)
- P11 - Statistical Analysis of Survival Data (24 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (594 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (65 KB)
- P40 - Survival Curves (442 KB)
- PA06_Organ_Weight_Summary (230 KB)
- PA48 - Summary_of_Tissue_Concentration (163 KB)
- PA48C - Tissue Concentration Curve (3 MB)
Chronic Individual Animal Data - Mice
- Female Individual Animal Body Weight Data (312 KB)
- Female Individual Animal Clinical Observations (29 KB)
- Female Individual Animal Neoplastic Pathology Data (145 KB)
- Female Individual Animal Non Neoplastic Pathology Data (507 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Individual Animal Organ Weight Data (24 KB)
- Individual Animal Tissue Concentration Data (19 KB)
- Individual Animal Urinalysis Data (19 KB)
- Male Individual Animal Body Weight Data (368 KB)
- Male Individual Animal Clinical Observations (73 KB)
- Male Individual Animal Neoplastic Pathology Data (145 KB)
- Male Individual Animal Non Neoplastic Pathology Data (612 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)
Genetic Toxicology
Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038B in B6C3F1 Mice
Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038C in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03038D
- G06 - Ames Summary Data (78 KB)
Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in DNA Damage Study G03038E in B6C3F1 Mice
- G01 - In Vivo Alkaline Comet Summary Data (91 KB)
- Individual Animal In Vivo Alkaline Comet Data (23 KB)