TR-603: Technical Report Pathology Tables and Curves
Pathology Tables, Survival and Growth Curves from NTP
Long-Term, Micronucleus Studies
TR-603: Black Cohosh
Long-Term
Chronic Study Tables - Rats
- Adjusted Pup Body Weights (177 KB)
- E01 - Animal Removal Summary By Treatment Group (12 KB)
- E01 - Animal Removal Summary By Treatment Group - Female Pup (7 KB)
- E01 - Animal Removal Summary By Treatment Group - Male Pup (7 KB)
- E02 - Animals Removed from Experiment (152 KB)
- E02 - Animals Removed from Experiment - Female Pup (127 KB)
- E02 - Animals Removed from Experiment - Male Pup (125 KB)
- E03 - Growth Curves (474 KB)
- E03 - Growth Curves - Female Pup (27 KB)
- E03 - Growth Curves - Male Pup (27 KB)
- E03 - Growth Curves Litter-based (63 KB)
- E04 - Mean Body Weights and Survival Table (23 KB)
- E04 - Mean Body Weights and Survival Table - Female Pup (8 KB)
- E04 - Mean Body Weights and Survival Table - Male Pup (8 KB)
- E04 - Mean Body Weights and Survival Table Litter-based (18 KB)
- E05 - Clinical Observations Summary (22 KB)
- E12 - Animal History - Female Pup (1 MB)
- E12 - Animal History -Male Pup (1 MB)
- Gestational Body Weights (30 KB)
- Lactational Body Weights (159 KB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (53 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (68 KB)
- P04 - Neoplasms by Individual Animal (661 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (50 KB)
- P08 - Statistical Analysis of Primary Tumors - Step Section with Litter Based Statistics (117 KB)
- P08 - Statistical Analysis of Primary Tumors Litter Based (222 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (934 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Litter-based (551 KB)
- P11 - Statistical Analysis of Survival Data (29 KB)
- P11 - Statistical Analysis of Survival Data - Litter-based (21 KB)
- P14 - Individual Animal Pathology Data (1 MB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (603 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (71 KB)
- P40 - Survival Curves (479 KB)
- P40 - Survival Curves - Female Pup (28 KB)
- P40 - Survival Curves - Male Pup (29 KB)
- PND 1 Litter Data (26 KB)
- PND 4 and 21 Live Litter Size and Survival (33 KB)
- R02 - Reproductive Performance Summary (37 KB)
Individual Animal Data - Rats
- Female Individual Animal Body Weight Data All Animals (383 KB)
- Female Individual Animal Body Weight Data All Animals - Female Pup (219 KB)
- Female Individual Animal Body Weight Data All Animals - Gestation (53 KB)
- Female Individual Animal Body Weight Data All Animals - Lactation (54 KB)
- Female Individual Animal Clinical Observations (199 KB)
- Female Individual Animal Neoplastic Pathology Data (121 KB)
- Female Individual Animal Non Neoplastic Pathology Data (740 KB)
- Female Individual Animal Survival Data (33 KB)
- Female Individual Animal Survival Data - Female Pup (118 KB)
- Female Individual Animal Terminal Body Weight Data (56 KB)
- Individual Animal Clinical Observations Data (9 KB)
- Individual Animal DamID and PupID Data (17 KB)
- Individual Animal Reproductive Performance Data (10 KB)
- Individual Pup Census and Litter Weight by Sex Data (23 KB)
- Male Individual Animal Body Weight Data All Animals (382 KB)
- Male Individual Animal Body Weight Data All Animals - Male Pup (232 KB)
- Male Individual Animal Clinical Observations (251 KB)
- Male Individual Animal Neoplastic Pathology Data (100 KB)
- Male Individual Animal Non Neoplastic Pathology Data (885 KB)
- Male Individual Animal Survival Data (33 KB)
- Male Individual Animal Survival Data - Male Pup (125 KB)
- Male Individual Animal Terminal Body Weight Data (56 KB)
3-Month Interim Study Tables - Mice
- E01 - Animal Removal Summary by Treatment Group (12 KB)
- E02 - Animals Removed from Experiment (33 KB)
- E03 - Growth Curves (212 KB)
- E04 - Mean Body Weights and Survival Table (10 KB)
- E05 - Clinical Observations Summary (16 KB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (13 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (11 KB)
- P04 - Neoplasms by Individual Animal (58 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (13 KB)
- P06 - Organ Weight Summary (12 KB)
- P08 - Statistical Analysis of Primary Tumors (8 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (55 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (7 KB)
- P11 - Statistical Analysis of Survival Data (13 KB)
- P12 - Organ Weights by Individual Animal (101 KB)
- P13 - Organ Weights by Treatment Group (19 KB)
- P14 - Individual Animal Pathology Data (68 KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (57 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (13 KB)
- P40 - Survival Curves (222 KB)
12-Month Interim Study Tables - Mice
- E01 - Animal Removal Summary by Treatment Group (8 KB)
- E02 - Animals Removed from Experiment (24 KB)
- E03 - Growth Curves (213 KB)
- E04 - Mean Body Weights and Survival Table (11 KB)
- E05 - Clinical Observations Summary (16 KB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (13 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (12 KB)
- P04 - Neoplasms by Individual Animal (57 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (13 KB)
- P06 - Organ Weight Summary (12 KB)
- P08 - Statistical Analysis of Primary Tumors (9 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (56 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (14 KB)
- P11 - Statistical Analysis of Survival Data (13 KB)
- P12 - Organ Weights by Individual Animal (101 KB)
- P13 - Organ Weights by Treatment Group (19 KB)
- P14 - Individual Animal Pathology Data (69 KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (57 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (13 KB)
- P40 - Survival Curves (220 KB)
Hematology and Bone Marrow and Spleen Organ Weight (3 and 12 Month) - Mice
- Abnormal Metarubicytes in Bone Marrow (26 KB)
- PA06 – Organ Weights Summary (44 KB)
- PA43 – Hematology Summary (268 KB)
- PA50 – Bone Marrow Smear Summary (161 KB)
Chronic Study Tables - Mice
- E01 - Animal Removal Summary By Treatment Group (8 KB)
- E02 - Animals Removed from Experiment (57 KB)
- E03 - TDMS Camera-Ready Growth Curve (245 KB)
- E04 - Mean Body Weights and Survival Table (13 KB)
- E05 - Clinical Observations Summary (16 KB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (26 KB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (30 KB)
- P04 - Neoplasms by Individual Animal (408 KB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (22 KB)
- P08 - Statistical Analysis of Primary Tumors (52 KB)
- P09 - Non-Neoplastic Lesions by Individual Animal (459 KB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (132 KB)
- P11 - Statistical Analysis of Survival Data (13 KB)
- P14 - Individual Animal Pathology Data (559 KB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (323 KB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30 KB)
- P40 - Survival Curves (231 KB)
Individual Animal Data - Mice
- Female Individual Animal Body Weight Data All Animals (577 KB)
- Female Individual Animal Clinical Observations (47 KB)
- Female Individual Animal Neoplastic Pathology Data (161 KB)
- Female Individual Animal Non Neoplastic Pathology Data (513 KB)
- Female Individual Animal Survival Data (56 KB)
- Female Individual Animal Terminal Body Weight Data (96 KB)
- Individual Animal Bone Marrow Smear Data (12 KB)
- Individual Animal Hematology Data (16 KB)
- Metarubicytes Data (18 KB)
Micronucleus
Genetic Toxicity Study G00058C
- G04 In Vivo Micronucleus Summary Data - 3 Month Interim (47 KB)
- Individual Animal In Vivo Micronucleus Data - 3 Month Interim (7 KB)
Genetic Toxicity Study G00058D
- G06 Ames Summary Data (74 KB)
Genetic Toxicity Study A13815
- G06 Ames Summary Data (238 KB)