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TR-603: Black cohosh (84776-26-1)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-603: Black cohosh (84776-26-1).
Micronucleus - Mice
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  • Female: Positive
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  • Female: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-603: Black cohosh (84776-26-1).
Bacterial Mutagenicity
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  • Negative
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  • Equivocal

Citation Information


NTP. TR-603: Black cohosh (84776-26-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-603 Toxicity Studies of Black Cohosh Administered via Oral Gavage to Harlan Sprague-Dawley Rats and B6C3F1/N Mice

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in HSD, Rat Exposed Via GAVAGE
Study Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C00058B) of Black Cohosh (84776-26-1 ) in B6C3F1/N, Mouse Exposed Via GAVAGE
Individual Animal Data
Hematology and Bone Marrow and Spleen Organ Weight (3 and 12 Month)
Chronic Study Tables
3-Month Interim Study Tables
12-Month Study Tables

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058C in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh (84776-26-1) in Micronucleus Study G00058E in B6C3F1 Mice
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A13815
Summary Data
Genetic Toxicity Evaluation of Black Cohosh in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G00058D
Summary Data