Reproductive and Developmental Toxicity Assessment of Butyl Paraben in Hsd: Sprague Dawley SD rats following Feed Exposure
https://doi.org/10.22427/NTP-DATA-NTP-DATA-RACB-BP
Note: The study data are being disseminated prior to external peer review under applicable information quality guidelines and do not represent and should not be construed to represent any final NTP determination or policy.
Reproductive Assessment Through Continuous Breeding
Dose Range Finding Study Tables
- I01 - Animal Removal Summary (45 KB)
- I03 - Growth Curve (1 MB)
- I03C - Growth Curve (1 MB)
- I04 - Mean Body Weight Summary (183 KB)
- I04G - Mean Body Weight Gain (60 KB)
- I05 - Clinical Observations Summary (91 KB)
- I05P - Pup Clinical Observations Summary (87 KB)
- I06 - Mean Feed Consumption (194 KB)
- I08 - Mean Test Compound Consumption (142 KB)
- R02 - Reproductive Performance Summary (48 KB)
- R03 - Summary of Litter Data (46 KB)
- R19 - Pup Mean Body Weight Summary (111 KB)
- R19C - Pup Growth Curves (783 KB)
- R19G - Pup Mean Body Weight Gain (88 KB)
- R20 - Pup Necropsy Summary (168 KB)
Dose Range Finding Individual Animal Data
- Individual Animal Body Weight Data (40 KB)
- Individual Animal Clinical Observations Data (132 KB)
- Individual Animal Consumption Data (61 KB)
- Individual Animal Gross Pathology Data (5 KB)
- Individual Animal Litter Data (14 KB)
- Individual Animal Pup Body Weight Data (32 KB)
- Individual Animal Pup Clinical Observations Data (66 KB)
- Individual Animal Pup Necropsy Data (8 KB)
- Individual Animal Removal Reasons Data (7 KB)
- Individual Animal Reproductive Performance Data (7 KB)
Main Study RACB Tables
- I01 - Animal Removal Summary (171 KB)
- I03 - Growth Curve (5 MB)
- I03C - Growth Curve (5 MB)
- I04 - Mean Body Weight Summary (1 MB)
- I04G - Mean Body Weight Gain (459 KB)
- I05 - Clinical Observations Summary (2 MB)
- I05P - Pup Clinical Observations Summary (833 KB)
- I06 - Mean Feed Consumption (1 MB)
- I08 - Mean Test Compound Intake (688 KB)
- I23 - Average Dose by Phase (88 KB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (704 KB)
- PA03R - Non-Neoplastic Lesion Summary with Percent and Litter Incidence (965 KB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (705 KB)
- PA06R - Organ Weights Summary (266 KB)
- PA08R - Statistical Analysis of Neoplastic Lesions with Litter Incidence (597 KB)
- PA10R - Statistical Analysis of Non-Neoplastic Lesions with Litter Incidence (972 KB)
- PA14 - Individual Animal Pathology Data (9 MB)
- PA18R - Non-Neoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (965 KB)
- PA46R Summary of Gross Pathology with Litter Summary (1 MB)
- R02 Reproductive Performance Summary (139 KB)
- R03 - Summary of Litter Data (207 KB)
- R04 - Anogenital Distance Summary (123 KB)
- R06 - Andrology Summary (109 KB)
- R14 - Developmental Markers Summary (144 KB)
- R16 - Pubertal Markers Summary (157 KB)
- R19 - Pup Mean Body Weight Summary (535 KB)
- R19C - Pup Growth Curve (5 MB)
- R19G - Pup Mean Body Weight Gain (371 KB)
- R20 - Pup Necropsy Summary (767 KB)
- R21 - Cross Generational Summary of Reproductive Performance (62 KB)
- R22 - Cross Generational Summary of Litters (71 KB)
- Vaginal Cytology Plots (583 KB)
- Vaginal Cytology Summary (282 KB)
- Vaginal Cytology Transition Matrix (438 KB)
Main Study RACB Individual Animal Data
- Individual Animal Andrology Data (32 KB)
- Individual Animal Body Weight Data (1 MB)
- Individual Animal Clinical Observations Data (4 MB)
- Individual Animal Consumption Data (1 MB)
- Individual Animal Developmental Markers Data (494 KB)
- Individual Animal Gross Pathology Data (483 KB)
- Individual Animal Histopathology Data (266 KB)
- Individual Animal Litter Crossover Data (13 KB)
- Individual Animal Litter Data (313 KB)
- Individual Animal Organ Weight Data (87 KB)
- Individual Animal Pup Body Weight Data (763 KB)
- Individual Animal Pup Clinical Observations Data (3 MB)
- Individual Animal Pup Necropsy Data (86 KB)
- Individual Animal Removal Reasons Data (65 KB)
- Individual Animal Reproductive Performance Crossover Data (6 KB)
- Individual Animal Reproductive Performance Data (32 KB)
- Individual Animal Vaginal Cytology Data (240 KB)