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Disposition and Metabolism of 2,2’-Dimorpholinodiethyl Ether in Harlan Sprague Dawley Rats and B6C3F1/N Mice after Oral, Intravenous Administration, and Dermal Application

Jacob D. McDonald, J. Michael Sanders, C. Edwin Garner, Melanie Doyle-Eisele, Benjamin C. Moeller and Suramya Waidyanatha

https://doi.org/10.22427/NTP-DATA-002-02085-0009-0000-6

Radiolabel Description:
Carbon-14 on the ring carbons adjacent to the nitrogen; 2,2'-Dimorpholinodiethyl ether, [morpholine-2,6-14C]-

Vehicles:
Intravenous, saline; Oral, purified water; Dermal, ethanol.


ADME Data


Data Summary - Male Rats

Data Summary - Female Rats

Data Summary - Male Mice

Data Summary - Female Mice