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TR-248: 4,4'-Methylenedianiline dihydrochloride (13552-44-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Positive, Male, Mice
View
  • Positive, Female, Mice

Citation Information


NTP. TR-248: 4,4'-Methylenedianiline dihydrochloride (13552-44-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-248 Carcinogenesis Studies of 4,4'-Methylenedianiline Dihydrochloride (CASRN 13552-44-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 4,4'-Methylenedianiline Dihydrochloride (13552-44-8) in Male F344 Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity of 4,4'-Methylenedianiline Dihydrochloride (13552-44-8) in Female F344 Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity of 4,4'-Methylenedianiline Dihydrochloride (13552-44-8) in Male B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity of 4,4'-Methylenedianiline Dihydrochloride (13552-44-8) in Female B6C3F1 Mice Exposed via Dosed Water