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TR-299: C.I. Disperse blue 1 (2475-45-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
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  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Equivocal Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-299: C.I. Disperse blue 1 (2475-45-8).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. TR-299: C.I. Disperse blue 1 (2475-45-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-299 Toxicology and Carcinogenesis Studies of C.I. Disperse Blue 1 (A commercial dye containing approximately 50% 1,4,5,8-tetraaminoanthraquinone, and 20% water) (CASRN 2475-45-8) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of C.I. Disperse Blue 1 (2475-45-8) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of C.I. Disperse Blue 1 (2475-45-8) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of C.I. Disperse Blue 1 (2475-45-8) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of C.I. Disperse Blue 1 (2475-45-8) in Female B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of C.I. Disperse Blue 1 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 336679
Summary Data