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TR-345: Roxarsone (121-19-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to TR-345: Roxarsone (121-19-7).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-345: Roxarsone (121-19-7).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-345: Roxarsone (121-19-7).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. TR-345: Roxarsone (121-19-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-345 Toxicology and Carcinogenesis Studies of Roxarsone (CASRN 121-19-7) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Roxarsone in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 195873
Summary Data