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TR-415: Polysorbate 80 (9005-65-6)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-415: Polysorbate 80 (9005-65-6).
Bacterial Mutagenicity
  • Negative

Citation Information

NTP. TR-415: Polysorbate 80 (9005-65-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).


TR-415 Toxicology and Carcinogenesis Studies of Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C60286) of Polysorbate 80 (Glycol) (9005-65-6) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C60286) of Polysorbate 80 (Glycol) (9005-65-6) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Polysorbate 80 (Glycol) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 405466
Summary Data