TR-425: Promethazine hydrochloride (58-33-3)
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
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| Drosophila Germ Cell Mutagenicity |
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Publications
TR-425
Toxicology and Carcinogenesis Studies of Promethazine Hydrochloride (CASRN 58-33-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity (C60673B) of Promethazine Hydrochloride (58-33-3) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C60673B) of Promethazine Hydrochloride (58-33-3) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Promethazine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 488601
Summary Data
- G06 - Ames Summary Data (155 KB)
Genetic Toxicity Evaluation of Promethazine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 767991
Summary Data
- G06 - Ames Summary Data (131 KB)