TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU)
Publications
TR-569
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC),Nevirapine(NVP) and Nelfinavir Mesylate (NFV) in B6C3F1 Mice (Transplacental Exposure Studies)
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Male B6C3F1/NCTR Mice via In-Utero Exposure
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (86 kB)
- P04 - Neoplasms by Individual Animal (775 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (75 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (856 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (96 kB)
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Female B6C3F1/NCTR Mice via In-Utero Exposure
Study Tables
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (85 kB)
- P04 - Neoplasms by Individual Animal (815 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (68 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (841 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (96 kB)
Individual Animal Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AIDS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 860655
Summary Data
- G06 - Ames Summary Data (148 KB)