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TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-569 Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC),Nevirapine(NVP) and Nelfinavir Mesylate (NFV) in B6C3F1 Mice (Transplacental Exposure Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Male B6C3F1/NCTR Mice via In-Utero Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Female B6C3F1/NCTR Mice via In-Utero Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AIDS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 860655
Summary Data