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TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU)

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU).
Bacterial Mutagenicity
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  • Positive

Citation Information

NTP. TR-569: AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-569 Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC),Nevirapine(NVP) and Nelfinavir Mesylate (NFV) in B6C3F1 Mice (Transplacental Exposure Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Male B6C3F1/NCTR Mice via In-Utero Exposure
Study Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C20311) of AZT/Drug Combinations Transplacental Carcinogenesis Study (AIDSTHERAPEU ) in Female B6C3F1/NCTR Mice via In-Utero Exposure
Study Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AIDS) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 860655
Summary Data