TR-573: Styrene-acrylonitrile trimer (SANTRIMER2)
Publications
TR-573
Toxicology and Carcinogenesis Study of Styrene-Acrylonitrile Trimer (CASRN SANTRIMER2) in F344/N Rats (Perinatal and Postnatal Feed Studies)
Study Data
Toxicity and Carcinogenicity Studies
7-Week (with Perinatal Exposure) Evaluation of the Toxicity (C99013) of Styrene-acrylonitrile Trimer (SANTRIMER2) in F344/N Rat Dams Exposed via Dosed Feed
18-Week (with Perinatal Exposure) Evaluation of the Toxicity (C99013) of Styrene-acrylonitrile Trimer (SANTRIMER2) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
7-Week (with Perinatal Exposure) Evaluation of the Toxicity (C99013) of Styrene-acrylonitrile Trimer (SANTRIMER2) in F344/N Rat Pups Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic (with Perinatal Exposure) Toxicity and Carcinogenicity (C99013) of Styrene-acrylonitrile Trimer (SANTRIMER2) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic (with Perinatal Exposure) Toxicity and Carcinogenicity (C99013) of Styrene-acrylonitrile Trimer (SANTRIMER2) in F344/N Rats Exposed via Dosed Feed
Study Tables
- E03 - Growth Curves (89 kB)
- E04 - Mean Body Weights and Survival Table (33 kB)
- E05 - Clinical Observations Summary (29 kB)
- E08 - Feed and Compound Consumption Table (41 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (59 kB)
- P04 - Neoplasms by Individual Animal (670 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (50 kB)
- P08 - Statistical Analysis of Primary Tumors (199 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (802 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal - Custom Report (Nerve Degeneration) (89 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (416 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions - Custom Report (Nerve Degeneration) (30 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (61 kB)
- P40 - Survival Curves (86 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (325 kB)
- Female Individual Animal Clinical Observations (251 kB)
- Female Individual Animal Neoplastic Pathology Data (125 kB)
- Female Individual Animal Non Neoplastic Pathology Data (726 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (346 kB)
- Male Individual Animal Clinical Observations (167 kB)
- Male Individual Animal Neoplastic Pathology Data (191 kB)
- Male Individual Animal Non Neoplastic Pathology Data (761 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Styrene-acrylonitrile Trimer (SANTRIMER2) in DNA Damage Study G99020C in F344/N Rats
Genetic Toxicity Evaluation of Styrene-acrylonitrile Trimer (SANTRIMER2) in Micronucleus Study G99020B in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Styrene-acrylonitrile Trimer in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A04901
Summary Data
- G06 - Ames Summary Data (86 KB)