1,2-Dichloroethane (107-06-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6020438
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
| Micronucleus - Mice |
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| Mammalian Cell Cytogenetics | |
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| CA | SCE |
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| Bacterial Mutagenicity |
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Publications
TOX-04
Toxicity Studies of 1,2-Dichloroethane (Ethylene Dichloride) in F344/N Rats, Sprague Dawley Rats, Osborne-Mendel Rats, and B6C3F1Mice (Drinking Water and Gavage Studies) (CASRN 107-06-2)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C00511B) of 1,2-Dichloroethane (107-06-2) in F344/N Rats Exposed via Gavage
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C00511C) of 1,2-Dichloroethane (107-06-2) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C00511D) of 1,2-Dichloroethane (107-06-2) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C00511D) of 1,2-Dichloroethane (107-06-2) in Osborne-Mendel Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C00511C) of 1,2-Dichloroethane (107-06-2) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloroethane (107-06-2) in Male Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloroethane (107-06-2) in Female Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloroethane (107-06-2) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,2-Dichloroethane (107-06-2) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Cytogenetic Study of 1,2-Dichloroethane in Chinese Hamster Ovary Cell Sister Chromatid Exchange Test
Genetic Toxicity Evaluation of 1,2-Dichloroethane (107-06-2) in Micronucleus Study A32670 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 1,2-Dichloroethane in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 446462
Summary Data
- G06 - Ames Summary Data (97 KB)