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Chlorinated paraffins: C23, 43% chlorine (108171-27-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7024823


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Male, Rats
View
  • Equivocal Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Male, Mice
View
  • Equivocal Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Chlorinated paraffins: C23, 43% chlorine (108171-27-3).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Chlorinated paraffins: C23, 43% chlorine (108171-27-3).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Chlorinated paraffins: C23, 43% chlorine (108171-27-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-305 Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C23, 43Chlorine) (CASRN 108171-27-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorinated Paraffins: C23, 43% Chlorine (108171-27-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorinated Paraffins: C23, 43% Chlorine (108171-27-3) in Female B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorinated Paraffins: C23, 43% Chlorine (108171-27-3) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlorinated Paraffins: C23, 43% Chlorine (108171-27-3) in Female F344 Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Chlorinated Paraffins: C23, 43% Chlorine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 104775
Summary Data