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tris(2-Chloroethyl) phosphate (115-96-8)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5021411


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • Equivocal Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to tris(2-Chloroethyl) phosphate (115-96-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to tris(2-Chloroethyl) phosphate (115-96-8).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. tris(2-Chloroethyl) phosphate (115-96-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-391 Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60128) of Tris(2-Chloroethyl) Phosphate (115-96-8 ) in F 344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C60128) of Tris(2-Chloroethyl) Phosphate (115-96-8 ) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of tris(2-Chloroethyl) Phosphate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 639784
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0183) of tris(2-Chloroethyl) phosphate (115-96-8) in F344 Rats Exposed via Gavage Administration
Screen for Developmental Toxicity in Zebrafish- Study 1
Results