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Butylated hydroxytoluene (128-37-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020216


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Butylated hydroxytoluene (128-37-0).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Butylated hydroxytoluene (128-37-0).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Butylated hydroxytoluene (128-37-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Butylated hydroxytoluene (128-37-0).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Butylated hydroxytoluene (128-37-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-150 Bioassay of Butylated Hydroxytoluene (BHT) for Possible Carcinogenicity (CASRN 128-37-0)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Butylated Hydroxytoluene (128-37-0) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butylated Hydroxytoluene (128-37-0) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butylated Hydroxytoluene (128-37-0) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Butylated Hydroxytoluene (128-37-0) in Female B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Butylated Hydroxytoluene (128-37-0) in Micronucleus Study A82929 in B6C3F1 Mice
Genetic Toxicity Evaluation of Butylated Hydroxytoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 377283
Summary Data