Trimethylolpropane triacrylate (15625-89-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0027773
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
| Micronucleus - Mice |
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| Bacterial Mutagenicity |
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Publications
TR-576
Toxicology and Carcinogenesis Studies of Trimethylolpropane triacrylate (CASRN 15625-89-5) in F344/N Rats (Topical Application Studies)
GMM-03
Toxicology Studies of Trimethylolpropane Triacrylate (Technical Grade) (CASRN 15625-89-5) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal Studies)
Study Data
Toxicity and Carcinogenicity Studies
2-Week Evaluation of the Toxicity (C88133) of Trimethylolpropane Triacrylate (15625-89-5) in F344/N Rats Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C88133) of Trimethylopropane Triacrylate (15625-89-5) in F344 Rats Exposed via Topical Application. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
2-Week Evaluation of the Toxicity (C88133) of Trimethylolpropane Triacrylate (15625-89-5) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C88133) of Trimethylopropane Triacrylate (15625-89-5) in B6C3F1 Mice Exposed via Topical Application. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
26-Week Evaluation of the Toxicity (C88133B) of Trimethylolpropane Triacrylate (15625-89-5) in Tg.AC Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C88133) of Trimethylolpropane Triacrylate (15625-89-5) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C88133) of Trimethylolpropane Triacrylate (15625-89-5) in F344/N Rats Exposed via Topical Application
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C88133) of Trimethylolpropane Triacrylate (15625-89-5) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C88133C) of Trimethylolpropane Triacrylate (15625-89-5) in F344/N Rats Exposed via Topical Application
Study Tables
- E03 - Growth Curves (80 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (25 kB)
- E09 - Summary of Dermal Clinical Observations at Site of Application (12 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (59 kB)
- P04 - Neoplasms by Individual Animal (1 mB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
- P08 - Statistical Analysis of Primary Tumors (261 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (608 kB)
- P11 - Statistical Analysis of Survival Data (28 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (882 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (61 kB)
- P40 - Survival Curves (86 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (525 kB)
- Female Individual Animal Clinical Observations (296 kB)
- Female Individual Animal Neoplastic Pathology Data (212 kB)
- Female Individual Animal Non Neoplastic Pathology Data (833 kB)
- Female Individual Animal Organ Weight Data (74 kB)
- Female Individual Animal Survival Data (44 kB)
- Male Individual Animal Body Weight Data (565 kB)
- Male Individual Animal Clinical Observations (186 kB)
- Male Individual Animal Neoplastic Pathology Data (336 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (74 kB)
- Male Individual Animal Survival Data (43 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C88133C) of Trimethylolpropane Triacrylate (15625-89-5) in B6C3F1 Mice Exposed via Topical Application
Study Tables
- E03 - Growth Curves (85 kB)
- E04 - Mean Body Weights and Survival Table (26 kB)
- E05 - Clinical Observations Summary (26 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (84 kB)
- P04 - Neoplasms by Individual Animal (792 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (60 kB)
- P08 - Statistical Analysis of Primary Tumors (239 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (848 kB)
- P11 - Statistical Analysis of Survival Data (26 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (682 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (87 kB)
- P40 - Survival Curves (85 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (484 kB)
- Female Individual Animal Clinical Observations (81 kB)
- Female Individual Animal Neoplastic Pathology Data (257 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (73 kB)
- Female Individual Animal Survival Data (44 kB)
- Male Individual Animal Body Weight Data (490 kB)
- Male Individual Animal Clinical Observations (105 kB)
- Male Individual Animal Neoplastic Pathology Data (189 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (73 kB)
- Male Individual Animal Survival Data (43 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Trimethylolpropane Triacrylate (15625-89-5) in Micronucleus Study A10307 in Tg.AC Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Trimethylolpropane Triacrylate (15625-89-5) in Micronucleus Study A71420 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Trimethylolpropane Triacrylate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A46551
Summary Data
- G06 - Ames Summary Data (69 KB)