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8-Methoxypsoralen (298-81-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
View
  • No Evidence, Female, Rats

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to 8-Methoxypsoralen (298-81-7).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 8-Methoxypsoralen (298-81-7).
Micronucleus - Mice
View
  • Male: Equivocal
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 8-Methoxypsoralen (298-81-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 8-Methoxypsoralen (298-81-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. 8-Methoxypsoralen (298-81-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-359 Toxicology and Carcinogenesis Studies of 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage Studies)
Final Report on the Developmental Toxicity of 8-Methoxypsoralen in New Zealand White Rabbits
Final Report on the Developmental Toxicity of 8-Methoxypsoralen in New Zealand White Rabbits
Final Report on the Developmental Toxicity of 8-Methoxypsoralen in Sprague-Dawley (CD) Rats

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of 8-Methoxypsoralen (298-81-7) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 8-Methoxypsoralen (298-81-7) in Female F344 Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 8-Methoxypsoralen (298-81-7) in Micronucleus Study 158726 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 8-Methoxypsoralen in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 773087
Summary Data

Other NTP Studies


Prenatal Developmental Toxicity Study (TER91016) of 8-Methoxypsoralen (298-81-7) in New Zealand White Rabbits Exposed via Gavage
Prenatal Developmental Toxicity Study (TER91017) of 8-Methoxypsoralen (298-81-7) in Sprague-Dawley Rats Exposed via Gavage