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2',3'-Didehydro-3'-deoxythymidine (3056-17-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1023819


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Micronucleus - Mice
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  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Bacterial Mutagenicity
View
  • Negative
View
  • Weakly Positive

Citation Information


NTP. 2',3'-Didehydro-3'-deoxythymidine (3056-17-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


IMM90016 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicological Evaluation Of AIDS Therapeutics, Task II-A Report: Dideoxydidehydrothymidine (d4T)
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine (3056-17-5) in Micronucleus Study 537402 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 420717
Summary Data
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41441
Summary Data