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2',3'-Didehydro-3'-deoxythymidine (3056-17-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1023819

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Bacterial Mutagenicity
View
  • Negative
View
  • Weakly Positive

Citation Information

NTP. 2',3'-Didehydro-3'-deoxythymidine (3056-17-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

IMM90016 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicological Evaluation Of AIDS Therapeutics, Task II-A Report: Dideoxydidehydrothymidine (d4T)
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine (3056-17-5) in Micronucleus Study 537402 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 420717
Summary Data
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41441
Summary Data

Other NTP Studies

30-Day Immunotoxicity Evaluation (IMM90016) of 2',3'-Didehydro-3'-Deoxythymidine (3056-17-5) in C57BL/6 Mice via Gavage
Individual and Summary Data
30-Day Immunotoxicity Evaluation (IMM90016) of 2',3'-Didehydro-3'-Deoxythymidine (3056-17-5) in DBA/2 Mice via Gavage
Individual and Summary Data
Toxicokinetic Evaluation (K3056175) of 2',3'-Didehydro-3'-deoxythymidine (D4T) (DTXSID1023819) in Mouse
Data

DTT Data Collections