COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

2',3'-Didehydro-3'-deoxythymidine (3056-17-5)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Micronucleus - Mice
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2',3'-Didehydro-3'-deoxythymidine (3056-17-5).
Bacterial Mutagenicity
View
  • Negative
View
  • Weakly Positive

Citation Information


NTP. 2',3'-Didehydro-3'-deoxythymidine (3056-17-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


IMM90016 NTP Summary Reports on Immunotoxicology Vol. 1, No. 1-15: Immunotoxicological Evaluation Of AIDS Therapeutics, Task II-A Report: Dideoxydidehydrothymidine (d4T)
Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine (3056-17-5) in Micronucleus Study 537402 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 420717
Summary Data
Genetic Toxicity Evaluation of 2',3'-Didehydro-3'-deoxythymidine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41441
Summary Data