Dibromoacetonitrile (3252-43-5)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3024940
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
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| Drosophila Germ Cell Mutagenicity |
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| Bacterial Mutagenicity |
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Publications
TR-544
Toxicology and Carcinogenesis Studies of Dibromoacetonitrile (CASRN 3252-43-5) in F344/N Rats and B6C3F1 Mice (Drinking Water studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Study Data
Toxicity and Carcinogenicity Studies
2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344 Rats Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Clinical Chemistry Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Clinical Chemistry Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in Micronucleus Study A00107 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 298559
Summary Data
- G06 - Ames Summary Data (196 KB)
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 450116
Summary Data
- G06 - Ames Summary Data (224 KB)
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 573952
Summary Data
- G06 - Ames Summary Data (244 KB)
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 877154
Summary Data
- G06 - Ames Summary Data (127 KB)
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44565
Summary Data
- G06 - Ames Summary Data (138 KB)