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Dibromoacetonitrile (3252-43-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3024940


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Dibromoacetonitrile (3252-43-5).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Dibromoacetonitrile (3252-43-5).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dibromoacetonitrile (3252-43-5).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Positive
View
  • Weakly Positive
View
  • Weakly Positive
View
  • Equivocal

Citation Information


NTP. Dibromoacetonitrile (3252-43-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-544 Toxicology and Carcinogenesis Studies of Dibromoacetonitrile (CASRN 3252-43-5) in F344/N Rats and B6C3F1 Mice (Drinking Water studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344 Rats Exposed via Dosed Water. NTP Special Study
2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water. NTP Special Study
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in Micronucleus Study A00107 in B6C3F1 Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 298559
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 450116
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 573952
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 877154
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44565
Summary Data