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TR-544: Dibromoacetonitrile (3252-43-5)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-544: Dibromoacetonitrile (3252-43-5).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-544: Dibromoacetonitrile (3252-43-5).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-544: Dibromoacetonitrile (3252-43-5).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Weakly Positive
View
  • Weakly Positive
View
  • Equivocal
View
  • Positive

Citation Information


NTP. TR-544: Dibromoacetonitrile (3252-43-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-544 Toxicology and Carcinogenesis Studies of Dibromoacetonitrile (CASRN 3252-43-5) in F344/N Rats and B6C3F1 Mice (Drinking Water studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
2-Week Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
3-Month Evaluation of the Toxicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in F344/N Rats Exposed via Dosed Water
Evaluation of the Chronic Toxicity and Carcinogenicity (C96015) of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in B6C3F1 Mice Exposed via Dosed Water

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) (3252-43-5) in Micronucleus Study A00107 in B6C3F1 Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 298559
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 450116
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 573952
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 877154
Summary Data
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Dibromoacetonitrile) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A44565
Summary Data