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Phenesterin (3546-10-9)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Phenesterin (3546-10-9).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Phenesterin (3546-10-9).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Phenesterin (3546-10-9).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Phenesterin (3546-10-9). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-060 Bioassay of Phenesterin for Possible Carcinogenicity (CASRN 3546-10-9)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Zimmering, S., Mason, J.M., and Valencia, R. Chemical mutagenesis testing in Drosophila. VII. Results of 22 coded compounds tested in larval feeding experiments. Environ. Molec. Mutagen. Vol. 14 (1989) 245-252

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Phenesterin (3546-10-9) in Male Sprague-Dawley Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenesterin (3546-10-9) in Female Sprague-Dawley Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenesterin (3546-10-9) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenesterin (3546-10-9) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Phenesterin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 461280
Summary Data
Genetic Toxicity Evaluation of Phenesterin in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 612071
Summary Data