Firemaster 680 (37853-59-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1024627
Publications
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, Sparrow B, Dunnick JK. Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat. Toxicol Lett. 2020 Oct 10;332:222-234. doi: 10.1016/j.toxlet.2020.07.016. Epub 2020 Jul 15. PMID: 32679240
Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, Sparrow B, Dunnick JK. Transcriptomic data from the rat liver after five days of exposure to legacy or emerging brominated flame retardants. Data Brief. 2020 Aug 5;32:106136. doi: 10.1016/j.dib.2020.106136. eCollection 2020 Oct. PMID: 32904430
Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat
Keith R Shockley, Michelle C Cora, David E Malarkey, Daven Jackson-Humbles, Molly Vallant, Brad J Collins, Esra Mutlu, Veronica G Robinson, Surayma Waidyanatha, Amy Zmarowski, Nicholas Machesky, Jamie Richey, Sam Harbo, Emily Cheng, Kristin Patton, Barney Sparrow, June K Dunnick
Toxicology Letters (2020) DOI: https://doi.org/10.1016/j.toxlet.2020.07.016 PMID: 32679240
GEO: GSE153366
Toxicology Letters (2020) DOI: https://doi.org/10.1016/j.toxlet.2020.07.016 PMID: 32679240
GEO: GSE153366
Study Data
Toxicity and Carcinogenicity Studies
5-Day Evaluation of the Toxicity (C20292-01) of Firemaster 680 (37853-59-1) in Sprague Dawley Rats Exposed via Gavage
Study Tables
- I01 - Animal Removal Summary (29 kB)
- I02 - Animal Removals (138 kB)
- I03 - Growth Curve (301 kB)
- I03C - Growth Curve (315 kB)
- I04 - Mean Body Weight Summary (74 kB)
- I05 - Clinical Observations Summary (32 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence (133 kB)
- PA03 - Non-Neoplastic Lesion Summary with Percent Incidence (110 kB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (134 kB)
- PA06 - Organ Weights Summary (87 kB)
- PA14 - Individual Animal Pathology Data (310 kB)
- PA18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grade (110 kB)
- PA41 - Clinical Chemistry Summary (145 kB)
- PA43 - Hematology Summary (156 kB)
- PA46 - Summary of Gross Pathology (230 kB)
- PA49 - Summary of Cytochrome Activity (52 kB)
- R07 - Hormone Summary (41 kB)
Individual Animal Data
- Individual Animal Body Weight Data (11 kB)
- Individual Animal Clinical Chemistry Data (9 kB)
- Individual Animal Clinical Observations Data (11 kB)
- Individual Animal Cytochrome Activity Data (8 kB)
- Individual Animal Gross Pathology Data (68 kB)
- Individual Animal Hematology Data (10 kB)
- Individual Animal Histopathology Data (5 kB)
- Individual Animal Hormone Data (6 kB)
- Individual Animal Organ Weight Data (8 kB)
- Individual Animal Removal Reasons Data (5 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Firemaster 680 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 068726
Summary Data
- G06 - Ames Summary Data (137 KB)