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2-Ethylhexyl p-methoxycinnamate (5466-77-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1025302


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 2-Ethylhexyl p-methoxycinnamate (5466-77-3).
Micronucleus - Rats
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Ethylhexyl p-methoxycinnamate (5466-77-3).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. 2-Ethylhexyl p-methoxycinnamate (5466-77-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


DART-06 NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive Performance, and Subchronic Assessments in F1 Offspring
Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
Metabolism and Disposition of 2-ethylhexyl-<i>p</i>-methoxycinnamate following Oral Gavage and Dermal Exposure in Harlan Sprague Dawley Rats and B6C3F1/N Mice and in Hepatocytes <i>in vitro</i> Timothy R. Fennell, James M. Mathews, Rodney W. Snyder, Yan Hong, Scott L. Watson, Sherry R. Black, Barry S. McIntyre, and Suramya Waidyanatha.
Xenobiotica (2017). DOI: https://doi.org/10.1080/00498254.2017.1400129 PMID: 29111853

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Ethylhexyl p-Methoxycinnamate (5466-77-3) in Micronucleus Study G20239B in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of 2-Ethylhexyl p-Methoxycinnamate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 201557
Summary Data
Genetic Toxicity Evaluation of 2-Ethylhexyl p-Methoxycinnamate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G20239
Summary Data

Other NTP Studies


Modified One Generation (MOG) Dose Range Finding Toxicity Study (MOG003) of 2-Ethylhexyl p-methoxycinnamate (5466-77-3) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Modified One Generation (MOG) Toxicity Study (MOG003B) of 2-Ethylhexyl p-methoxycinnamate (5466-77-3) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Study Tables
Individual Animal Data