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Phenoxybenzamine hydrochloride (63-92-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0021127

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Phenoxybenzamine hydrochloride (63-92-3).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Phenoxybenzamine hydrochloride (63-92-3).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. Phenoxybenzamine hydrochloride (63-92-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-072 Bioassay of Phenoxybenzamine Hydrochloride for Possible Carcinogenicity (CASRN 63-92-3)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Phenoxybenzamine Hydrochloride (63-92-3) in Male Sprague-Dawley Rats Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenoxybenzamine Hydrochloride (63-92-3) in Female Sprague-Dawley Rats Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenoxybenzamine Hydrochloride (63-92-3) in Male B6C3F1 Mice Exposed via Intraperitoneal Injection
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Phenoxybenzamine Hydrochloride (63-92-3) in Female B6C3F1 Mice Exposed via Intraperitoneal Injection
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Phenoxybenzamine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 695265
Summary Data

DTT Data Collections