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Dimorpholinodiethyl ether (6425-39-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9042170

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dimorpholinodiethyl ether (6425-39-4).
Bacterial Mutagenicity
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  • Negative
View
  • Negative

Citation Information

NTP. Dimorpholinodiethyl ether (6425-39-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Disposition and Metabolism of 2,2’-Dimorpholinodiethyl Ether in Harlan Sprague Dawley Rats and B6C3F1/N Mice after Oral, Intravenous Administration, and Dermal Application Jacob D. McDonald, J. Michael Sanders, C. Edwin Garner, Melanie Doyle-Eisele, Benjamin C. Moeller and Suramya Waidyanatha

https://doi.org/10.22427/NTP-DATA-002-02085-0009-0000-6

Radiolabel Description:
Carbon-14 on the ring carbons adjacent to the nitrogen; 2,2'-Dimorpholinodiethyl ether, [morpholine-2,6-14C]-

Vehicles:
Intravenous, saline; Oral, purified water; Dermal, ethanol.
Evaluation of 2,2’-Dimorpholinodiethyl Ether (DMDEE) in Pathology, Perinatal, and Genotoxicity Studies Authors: Rachel Frawleya, Stephanie L. Smith-Roea, Helen Cunnya, Karr Stinsonb, Guanhua Xiec, Barry McIntyrea, Karen Cimond

Affiliations:
a National Institute of Environmental Health Sciences, NIH, P.O. Box 12233, Research Triangle Park, NC, USA 27709
b Southern Research, 2000 9th Avenue S, Birmingham, AL, USA 35294
c Social & Scientific Systems, Inc., 4505 Emperor Blvd, Suite 400, Durham, NC, USA 27703
d Environmental Pathology Laboratories, Inc., 45600 Terminal Dr. #100, Sterling, VA, USA 20166

Corresponding author: Rachel Frawley, Division of Translational Toxicology, National Institute of Environmental Health Sciences, NIH, P.O. Box 12233, Research Triangle Park, NC, USA 27709, 984-287-3132, frawleyr@niehs.nih.gov

DOI: https://doi.org/10.22427/NTP-DATA-500-108-001-000-5

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 2,2'-Dimorpholinodiethyl Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G06065
Summary Data
Genetic Toxicity Evaluation of 2,2'-Dimorpholinodiethyl Ether (DMDEE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G06065B
Summary Data

DTT Data Collections