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Dimorpholinodiethyl ether (6425-39-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9042170


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Dimorpholinodiethyl ether (6425-39-4).
Bacterial Mutagenicity
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  • Negative
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  • Negative

Citation Information


NTP. Dimorpholinodiethyl ether (6425-39-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Disposition and Metabolism of 2,2’-Dimorpholinodiethyl Ether in Harlan Sprague Dawley Rats and B6C3F1/N Mice after Oral, Intravenous Administration, and Dermal Application Jacob D. McDonald, J. Michael Sanders, C. Edwin Garner, Melanie Doyle-Eisele, Benjamin C. Moeller and Suramya Waidyanatha

https://doi.org/10.22427/NTP-DATA-002-02085-0009-0000-6

Radiolabel Description:
Carbon-14 on the ring carbons adjacent to the nitrogen; 2,2'-Dimorpholinodiethyl ether, [morpholine-2,6-14C]-

Vehicles:
Intravenous, saline; Oral, purified water; Dermal, ethanol.

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2,2'-Dimorpholinodiethyl Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G06065
Summary Data
Genetic Toxicity Evaluation of 2,2'-Dimorpholinodiethyl Ether (DMDEE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G06065B
Summary Data