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Formamide (75-12-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8025337


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Male, Mice
  • Equivocal Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Formamide (75-12-7).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Formamide (75-12-7).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Formamide (75-12-7).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Negative

Citation Information


NTP. Formamide (75-12-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-541 Toxicology and Carcinogenesis Studies of Formamide (CASRN 75-12-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
TER98002
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Final Report on the Developmental Toxicity of Formamide (CAS# 75-12-7) Administered by Gavage to Sprague-Dawley CD Rats on Gestational Days 6-19
Developmental Toxicity Evaluation of Formamide (CASRN 75-12-7) Administered by Gavage to New Zealand White Rabbits on Gestational Days 6 through 29.

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in F344 Rats Exposed via Gavage. NTP Special Study
2-Week Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C88123B) of Formamide (75-12-7) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C88123B) of Formamide (75-12-7) in B6C3F1 Mice Exposed via Gavage
Special Evaluation of the Toxicity (C88123) of Formamide (75-12-7) in F344/N Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Formamide (75-12-7) in Micronucleus Study A14799 in B6C3F1 Mice
Genetic Toxicity Evaluation of Formamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 096297
Summary Data
Genetic Toxicity Evaluation of Formamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 799767
Summary Data
Genetic Toxicity Evaluation of Formamide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A95988
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0533) of Formamide (75-12-7) in F344 Rats and B6C3F1 Mice Exposed via Intravenous Injection or Nose-Only Respiratory Exposure
Prenatal Developmental Toxicity Pilot Study (TRP97008) of Formamide (75-12-7) in Sprague-Dawley Rats Exposed via Gavage
Prenatal Developmental Toxicity Pilot Study (TRP98002) of Formamide (75-12-7) in New Zealand White Rabbits Exposed via Gavage
Prenatal Developmental Toxicity Study (TER97002) of Formamide (75-12-7) in Sprague-Dawley Rats Exposed via Gavage
Prenatal Developmental Toxicity Study (TER98002) of Formamide (75-12-7) in New Zealand White Rabbits Exposed via Gavage