2,4-Dichlorophenoxyacetic acid (94-75-7)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020442
Publications
Mortelmans, K., Haworth, S., Speck, W., and Zeiger, E. Mutagenicity testing of Agent Orange components and related chemicals Toxicology and Applied Pharmacology Vol. 75 (1984) 137-146
Zimmering, S., Mason, J.M., Valencia, R., and Woodruff, R.C. Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 87-100
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Sprague-Dawley Rats Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Syrian Golden Hamsters Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Syrian Golden Hamsters Exposed via Dosed Feed
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E08 - Feed, Water, And Compound Consumption Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Syrian Golden Hamsters Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C93027C) of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) (94-75-7) in Syrian Golden Hamsters Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 541375
Summary Data
- G06 - Ames Summary Data (239 KB)
Genetic Toxicity Evaluation of Peroxisome Project (2,4-Dichlorophenoxyacetic Acid) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 843375
Summary Data
- G06 - Ames Summary Data (132 KB)
Other NTP Studies
Toxicokinetic Evaluation (S0546) of 2-4-dichlorophenoxyacetic acid (DTXSID0020442) in Rat, Mouse and Hamster
Data
- Annotated Group Parameters (20 kB)
- Annotated Individual Animal Data (134 kB)
- Original Data (63 kB)
- Summary Data - Hamster (111 kB)
- Summary Data - Mouse (135 kB)
- Summary Data - Rat (143 kB)