U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

o-Chloroaniline (95-51-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2021810


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to o-Chloroaniline (95-51-2).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to o-Chloroaniline (95-51-2).
Micronucleus - Rats
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to o-Chloroaniline (95-51-2).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to o-Chloroaniline (95-51-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. o-Chloroaniline (95-51-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-43 Comparative Toxicity Studies of o-,m-, and p-Chloroanilines (CASRNs 95-51-2; 108-42-9; and 106-47-8) Administered by Gavage to F344/N Rats and B6C3F1Mice
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A07291 in B6C3F1 Mice
Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A49067 in B6C3F1 Mice
Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A89139 in F344 Rats
Genetic Toxicity Evaluation of o-Chloroaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 184572
Summary Data
Genetic Toxicity Evaluation of o-Chloroaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 191170
Summary Data