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o-Chloroaniline (95-51-2)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to o-Chloroaniline (95-51-2).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to o-Chloroaniline (95-51-2).
Micronucleus - Rats
View
  • Male: Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to o-Chloroaniline (95-51-2).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to o-Chloroaniline (95-51-2).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. o-Chloroaniline (95-51-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-43 Comparative Toxicity Studies of o-,m-, and p-Chloroanilines (CASRNs 95-51-2; 108-42-9; and 106-47-8) Administered by Gavage to F344/N Rats and B6C3F1Mice
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in F344 Rats Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in B6C3F1 Mice Exposed via Gavage. NTP Special Study
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C91001) of o-Chloroaniline (95-51-2) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A07291 in B6C3F1 Mice
Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A49067 in B6C3F1 Mice
Genetic Toxicity Evaluation of o-Chloroaniline (95-51-2) in Micronucleus Study A89139 in F344 Rats
Genetic Toxicity Evaluation of o-Chloroaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 184572
Summary Data
Genetic Toxicity Evaluation of o-Chloroaniline in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 191170
Summary Data