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Crude MCHM (CRUDEMCHM)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Crude MCHM (CRUDEMCHM).
Micronucleus - Rats
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  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Crude MCHM (CRUDEMCHM).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Crude MCHM (CRUDEMCHM). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


IMM-01 NTP Technical Report on the Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclohexanemethanol (CAS No. 34885-03-5) and Crude 4-Methylcyclohexanemethanol Administered Topically to Female BALB/c Mice
Evaluation of 4-methylcyclohexanemethanol (MCHM) in a Combined Irritancy and Local Lymph Node Assay (LLNA) in Mice Johnson VJ, Auerbach SS, Luster MI, Waidyanatha S, Masten SA, Wolfe MS, Burleson FG, Burleson GR, Germolec DR.
Food and Chemical Toxicology (2017) DOI: https://doi.org/10.1016/j.fct.2017.03.034 PMID: 28343035

Study Data


Toxicity and Carcinogenicity Studies


Benchmark Dose Analysis of NTP Elk River, West Virginia Chemical Spill-Associated Samples

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Crude MCHM (CRUDEMCHM) in Micronucleus Study G14013 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of Crude MCHM in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G14013B
Summary Data

Other NTP Studies


5-Day Toxicogenomic Evaluation of Crude 4-Methylcyclohexanemethanol (CRUDEMCHM) in Male Harlan Sprague Dawley Rats Exposed via Gavage
Immunological Evaluation of Crude and Pure MCHM in a Combined Irritation and Local Lymph Node Assay (LLNA) in Female BALB/c Mice (dermal studies)
Zebrafish Embryo and Larval Photomotor Response for NTP Elk River, West Virginia chemical spill-associated samples
Zebrafish Photomotor Response Study
Zebrafish Developmental Toxicity Study
Documentation