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Abrasive Blasting Agents

Citation Information

NTP. Abrasive Blasting Agents. Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

TOX-91 Toxicity Studies of Abrasive Blasting Agents Blasting Sand,Coal Slag, Crushed Glass, Garnet and Specular Hematite (CASRN BLASTINGSAND,COALSLAG,CRUSHEDGLASS,GARNET and HEMATITESPEC) Administered by Inhalation to F344/NTac and Harlan Sprague-Dawley Rats

Study Data

Protocol

Toxicity and Carcinogenicity Studies

39-Week Evaluation of the Toxicity (C20213) of Abrasive Blasting Agents: Blasting Sand (BLASTINGSAND) in Harlan Sprague-Dawley Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (217 kB)
E04 - Mean Body Weights and Survival Table (14 kB)
E05 - Clinical Observations Summary (12 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (19 kB)
P04 - Neoplasms by Individual Animal (66 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (21 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (79 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (72 kB)
P14 - Individual Animal Pathology Data (295 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 kB)
P40 - Survival Curves (213 kB)

Interim (4 Week) Study Tables

Interim (26 Week) Study Tables

Interim (16 Week) Study Tables

Individual Animal Data

Male Individual Animal Body Weight Data (125 kB)
Male Individual Animal Clinical Observations (3 kB)
Male Individual Animal Non Neoplastic Pathology Data (272 kB)
Male Individual Animal Organ Weight Data (70 kB)
Male Individual Animal Survival Data (25 kB)

39-Week Evaluation of the Toxicity (C20536) of Abrasive Blasting Agents: Specular Hematite (HEMATITESPEC) in Harlan Sprague-Dawley Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (217 kB)
E04 - Mean Body Weights and Survival Table (14 kB)
E05 - Clinical Observations Summary (12 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (20 kB)
P04 - Neoplasms by Individual Animal (62 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (21 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (80 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (87 kB)
P14 - Individual Animal Pathology Data (296 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (20 kB)
P40 - Survival Curves (205 kB)

Interim (4 Week) Study Tables

Interim (26 Week) Study Tables

Interim (16 Week) Study Tables

Individual Animal Data

Male Individual Animal Body Weight Data (120 kB)
Male Individual Animal Clinical Observations (4 kB)
Male Individual Animal Neoplastic Pathology Data (3 kB)
Male Individual Animal Non Neoplastic Pathology Data (303 kB)
Male Individual Animal Organ Weight Data (70 kB)
Male Individual Animal Survival Data (25 kB)

2-Week Evaluation of the Toxicity (C20532) of Abrasive Blasting Agents (Coal Slag) (COALSLAG) in F344/N Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (172 kB)
E04 - Mean Body Weights and Survival Table (14 kB)
E05 - Clinical Observations Summary (12 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 kB)
P04 - Neoplasms by Individual Animal (60 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (60 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (28 kB)
P14 - Individual Animal Pathology Data (51 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 kB)
P40 - Survival Curves (192 kB)

Individual Animal Data

Male Individual Animal Body Weight Data (7 kB)
Male Individual Animal Non Neoplastic Pathology Data (9 kB)
Male Individual Animal Survival Data (5 kB)
Male Individual Animal Terminal_Body Weight Data (8 kB)
Male Individual Clinical Observations (2 kB)

2-Week Evaluation of the Toxicity (C20533) of Abrasive Blasting Agents (Garnet) (GARNET) in F344/N Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (169 kB)
E04 - Mean Body Weights and Survival Table (13 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (17 kB)
P04 - Neoplasms by Individual Animal (58 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (59 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (21 kB)
P14 - Individual Animal Pathology Data (51 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (17 kB)
P40 - Survival Curves (186 kB)

Individual Animal Data

Male Individual Animal Body Weight Data (7 kB)
Male Individual Animal Non Neoplastic Pathology Data (11 kB)
Male Individual Animal Survival Data (5 kB)
Male Individual Animal Terminal_Body Weight Data (8 kB)

2-Week Evaluation of the Toxicity (C20213) of Abrasive Blasting Agents: Blasting Sand (BLASTINGSAND) in F344/NTac Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (180 kB)
E04 - Mean Body Weights and Survival Table (13 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 kB)
P04 - Neoplasms by Individual Animal (60 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (60 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (21 kB)
P14 - Individual Animal Pathology Data (51 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 kB)
P40 - Survival Curves (201 kB)

Individual Animal Data

Male Individual Animal Body Weight Data (7 kB)
Male Individual Animal Non Neoplastic Pathology Data (7 kB)
Male Individual Animal Survival Data (5 kB)
Male Individual Animal Terminal_Body Weight Data (8 kB)

2-Week Evaluation of the Toxicity (C20534) of Abrasive Blasting Agents (Crushed Glass) (CRUSHEDGLASS) in F344/NTac Rats via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (158 kB)
E04 - Mean Body Weights and Survival Table (13 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (20 kB)
P04 - Neoplasms by Individual Animal (58 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (58 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (26 kB)
P14 - Individual Animal Pathology Data (52 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 kB)
P40 - Survival Curves (192 kB)

Individual Animal Data

Male Individual Animal Body Weight Data (7 kB)
Male Individual Animal Non Neoplastic Pathology Data (17 kB)
Male Individual Animal Survival Data (5 kB)
Male Individual Animal Terminal_Body Weight Data (8 kB)

2-Week Evaluation of the Toxicity (C20536) of Abrasive Blasting Agents: Specular Hematite (HEMATITESPEC ) in F344/N Tac, Rat Exposed via Whole Body Respiratory Exposure

Study Tables

E03 - Growth Curves (175 kB)
E04 - Mean Body Weights and Survival Table (13 kB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (18 kB)
P04 - Neoplasms by Individual Animal (70 kB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (19 kB)
P09 - Non-Neoplastic Lesions by Individual Animal (71 kB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (24 kB)
P14 - Individual Animal Pathology Data (64 kB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (19 kB)
P40 - Survival Curves (194 kB)

Individual Animal Data

Male Individual Animal Body Weight Data (8 kB)
Male Individual Animal Non Neoplastic Pathology Data (14 kB)
Male Individual Animal Survival Data (6 kB)
Male Individual Animal Terminal_Body Weight Data (9 kB)