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GMM-05: Bromodichloromethane (75-27-4)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to GMM-05: Bromodichloromethane (75-27-4).
Micronucleus - Mice
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  • Male: Negative
    Female: Negative
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  • Male: Equivocal
    Female: Negative
View
  • Male: Equivocal
    Female: Equivocal
View
  • Male: Negative
    Female: Negative
View
  • Male: Equivocal
    Female: Negative

Citation Information


NTP. GMM-05: Bromodichloromethane (75-27-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


GMM-05 Toxicology Studies of Bromodichloromethane (CASRN 75-27-4) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C97013F) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in FVB/N Mice Exposed via Topical Application
26-39 Week Evaluation of the Toxicity (C97013J) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in P53(C57BL/6) Mice Exposed via Dosed Water
26-39 Week Evaluation of the Toxicity (C97013K) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in P53(C57BL/6) Mice Exposed via Gavage
26-Week Evaluation of the Toxicity (C97013E) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in P53(C57BL/6) Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C97013G) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in P53(C57BL/6) Mice Exposed via Gavage
26-39 Week Evaluation of the Toxicity (C97013J) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Dosed Water
26-39 Week Evaluation of the Toxicity (C97013K) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Gavage
26-Week Evaluation of the Toxicity (C97013E) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Dosed Water
26-Week Evaluation of the Toxicity (C97013F) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Topical Application
26-Week Evaluation of the Toxicity (C97013F) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Topical Application
26-Week Evaluation of the Toxicity (C97013G) of Water Disinfection Model (Bromodichloromethane) (75-27-4) in Tg.AC Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Water Disinfection Byproducts (Bromodichloromethane) (75-27-4) in Micronucleus Study A08959 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Bromodichloromethane) (75-27-4) in Micronucleus Study A38548 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Bromodichloromethane) (75-27-4) in Micronucleus Study A39408 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Bromodichloromethane) (75-27-4) in Micronucleus Study A55870 in P53 +/- (C57BL/6) Mice
Genetic Toxicity Evaluation of Water Disinfection Byproducts (Bromodichloromethane) (75-27-4) in Micronucleus Study A90924 in P53 +/- (C57BL/6) Mice