U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

GMM-09: Dicyclohexylcarbodiimide (538-75-0)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to GMM-09: Dicyclohexylcarbodiimide (538-75-0).
Micronucleus - Mice
View
  • Male: Weakly Positive
    Female: Weakly Positive
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to GMM-09: Dicyclohexylcarbodiimide (538-75-0).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to GMM-09: Dicyclohexylcarbodiimide (538-75-0).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. GMM-09: Dicyclohexylcarbodiimide (538-75-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


GMM-09 Toxicology Studies of Dicyclohexylcarbodiimide (CASRN 538-75-0) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Dermal Studies)

Study Data


Toxicity and Carcinogenicity Studies


150-Day Evaluation of the Toxicity (C93021B) of Dicyclohexylcarbodiimide (538-75-0) in Tg.AC Mice Exposed via Topical Application
2-Week Evaluation of the Toxicity (C93021) of Dicyclohexylcarbodiimide (538-75-0) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C93021) of Dicyclohexylcarbodiimide (538-75-0) in B6C3F1 Mice Exposed via Topical Application
26-Week Evaluation of the Toxicity (C93021C) of Dicyclohexylcarbodiimide (538-75-0) in P53(C57BL/6) Mice Exposed via Topical Application
3-Month Evaluation of the Toxicity (C93021) of Dicyclohexylcarbodiimide (538-75-0) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C93021) of Dicyclohexylcarbodiimide (538-75-0) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Dicyclohexylcarbodiimide (538-75-0) in Micronucleus Study A45449 in F344 Rats
Genetic Toxicity Evaluation of Dicyclohexylcarbodiimide (538-75-0) in Micronucleus Study A63966 in B6C3F1 Mice
Genetic Toxicity Evaluation of Dicyclohexylcarbodiimide in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A46724
Summary Data