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GMM-15: Senna (8013-11-4)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to GMM-15: Senna (8013-11-4).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to GMM-15: Senna (8013-11-4).
Bacterial Mutagenicity
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  • Positive
View
  • Positive
View
  • Negative
View
  • Negative

Citation Information


NTP. GMM-15: Senna (8013-11-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


GMM-15 Toxicology Study of Senna (CASRN 8013-11-4) in C57BL/6NTac Mice and Toxicology and Carcinogenesis Study of Senna in Genetically Modified C3B6.129F1/Tac-Trp53tm1Brd N12 Haploinsufficient Mice (Feed Studies)

Study Data


Toxicity and Carcinogenicity Studies


18-33 Day Evaluation of the Toxicity (C20101) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed
26-39 Week Evaluation of the Toxicity (C20101B) of Senna (Powdered) (8013-11-4) in P53(C57BL/6) Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Senna (Powdered) (8013-11-4) in Micronucleus Study GEMT28 in P53 +/- (C57BL/6) Mice
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 840294
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A09328
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A10901
Summary Data
Genetic Toxicity Evaluation of Senna (Powdered) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study GEMT28B
Summary Data