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TOX-67: 4-Methylimidazole (822-36-6), 2-Methylimidazole (693-98-1)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TOX-67: 4-Methylimidazole (822-36-6), 2-Methylimidazole (693-98-1).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
View
  • Male: Positive
    Female: Positive
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TOX-67: 4-Methylimidazole (822-36-6), 2-Methylimidazole (693-98-1).
Micronucleus - Rats
View
  • Male: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TOX-67: 4-Methylimidazole (822-36-6), 2-Methylimidazole (693-98-1).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative
View
  • Negative

Citation Information


NTP. TOX-67: 4-Methylimidazole (822-36-6), 2-Methylimidazole (693-98-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-67 Toxicity Studies of 2-Methylimidazole and 4-Methylimidazole Administered in Feed to F344/N Rats and B6C3F1Mice (CASRN 693-98-1 and 822-36-6)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in F344/N Rats Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C92013) of 4-Methylimidazole (822-36-6) in F344/N Rats Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed
2-Week Evaluation of the Toxicity (C92013) of 4-Methylimidazole (822-36-6) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92013) of 4-Methylimidazole (822-36-6) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92013) of 4-Methylimidazole (822-36-6) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A05124 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A69851 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A84932 in F344 Rats
Genetic Toxicity Evaluation of 2-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A28742
Summary Data
Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A12637 in B6C3F1 Mice
Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A38684 in F344 Rats
Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A49564 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 4-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41578
Summary Data
Genetic Toxicity Evaluation of 4-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A53668
Summary Data