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TR-080: 1,4-Dioxane (123-91-1)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Citation Information

NTP. TR-080: 1,4-Dioxane (123-91-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-080 Bioassay of 1,4-Dioxane for Possible Carcinogenicity (CASRN 123-91-1)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,4-Dioxane (123-91-1) in Male Osborne-Mendel Rats Exposed via Dosed Water
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,4-Dioxane (123-91-1) in Female Osborne-Mendel Rats Exposed via Dosed Water
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,4-Dioxane (123-91-1) in Male B6C3F1 Mice Exposed via Dosed Water
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,4-Dioxane (123-91-1) in Female B6C3F1 Mice Exposed via Dosed Water
Individual Animal Data