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TR-269: 1,3-Dichloro-1-propene (542-75-6)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Male, Rats
View
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Inadequate Study, Male, Mice
View
  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-269: 1,3-Dichloro-1-propene (542-75-6).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-269: 1,3-Dichloro-1-propene (542-75-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. TR-269: 1,3-Dichloro-1-propene (542-75-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-269 Toxicology and Carcinogenesis Studies of Telone® (Technical-Grade 1,3-Dichloropropane [CASRN 542-75-6] Containing 1.0 Epichlorohydrin as a Stabilizer) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Dichloropropene (Telone II) (542-75-6) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Dichloropropene (Telone II) (542-75-6) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Dichloropropene (Telone II) (542-75-6) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of 1,3-Dichloropropene (Telone II) (542-75-6) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 1,3-Dichloropropene (Telone II) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 172972
Summary Data