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TR-289: Benzene (71-43-2)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
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  • Clear Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Male, Mice
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  • Clear Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-289: Benzene (71-43-2).
Micronucleus - Mice
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  • Male: Positive
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  • Male: Positive
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  • Male: Positive

Citation Information

NTP. TR-289: Benzene (71-43-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-289 Toxicology and Carcinogenesis Studies of Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of Benzene (71-43-2) in Male F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzene (71-43-2) in Female F344 Rats Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzene (71-43-2) in Male B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of Benzene (71-43-2) in Female B6C3F1 Mice Exposed via Gavage
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Benzene (71-43-2) in Micronucleus Study 516923 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Benzene (71-43-2) in Micronucleus Study A48141 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Benzene (71-43-2) in Micronucleus Study A60851 in B6C3F1 Mice
Summary and Individual Animal Data