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TR-451: Nickel (II) oxide (1313-99-1)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Some Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Equivocal Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-451: Nickel (II) oxide (1313-99-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative

Citation Information

NTP. TR-451: Nickel (II) oxide (1313-99-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-451 Toxicology and Carcinogenesis Studies of Nickel Oxide (CASRN 1313-99-1) in F344 Rats and B6C3F1 Mice (Inhalation Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C00862) of Nickel (II) Oxide (1313-99-1) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C00862) of Nickel (II) Oxide (1313-99-1) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Nickel (II) Oxide (1313-99-1) in Micronucleus Study A32705 in B6C3F1 Mice
Summary and Individual Animal Data