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TR-467: Chloroprene (126-99-8)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to TR-467: Chloroprene (126-99-8).
Rodent Cytogenetics
CA
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-467: Chloroprene (126-99-8).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Female: Negative
View
  • Female: Negative
View
  • Male: Negative (Nonstandard Protocol)
View
  • Female: Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-467: Chloroprene (126-99-8).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-467: Chloroprene (126-99-8).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. TR-467: Chloroprene (126-99-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-467 Toxicology and Carcinogenesis Studies of Chloroprene (CASRN 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


26-Week Evaluation of the Toxicity (C50522C) of Chloroprene (126-99-8) in P53(C57BL/6) Mice via Whole Body Respiratory Exposure
26-Week Evaluation of the Toxicity (C50522D) of Chloroprene (126-99-8) in Tg.AC Mice via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C50522) of Chloroprene (126-99-8) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C50522) of Chloroprene (126-99-8) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C50522B) of Chloroprene (126-99-8) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C50522B) of Chloroprene (126-99-8) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Chloroprene (126-99-8) in Micronucleus Study A18069 in Tg.AC (FVB/N) Mice
Genetic Toxicity Evaluation of Chloroprene (126-99-8) in Micronucleus Study A73731 in Mice
Genetic Toxicity Evaluation of Chloroprene (126-99-8) in Micronucleus Study A74378 in B6C3F1 Mice
Genetic Toxicity Evaluation of Chloroprene (126-99-8) in Micronucleus Study A75483 in Mice
Genetic Toxicity Evaluation of Chloroprene (126-99-8) in Micronucleus Study A84893 in B6C3F1 Mice
Genetic Toxicity Evaluation of Chloroprene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 703184
Summary Data