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TR-497: Methacrylonitrile (126-98-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-497: Methacrylonitrile (126-98-7).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-497: Methacrylonitrile (126-98-7).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TR-497: Methacrylonitrile (126-98-7).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-497: Methacrylonitrile (126-98-7).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. TR-497: Methacrylonitrile (126-98-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-497 Toxicology and Carcinogenesis Studies of Methacrylonitrile (CASRN 126-98-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C88050B) of Methacrylonitrile (126-98-7) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C88050B) of Methacrylonitrile (126-98-7) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Methacrylonitrile (126-98-7) in Micronucleus Study A05400 in F344 Rats
Genetic Toxicity Evaluation of Methacrylonitrile (126-98-7) in Micronucleus Study A38969 in B6C3F1 Mice
Genetic Toxicity Evaluation of Methacrylonitrile (126-98-7) in Micronucleus Study A63179 in B6C3F1 Mice
Genetic Toxicity Evaluation of Methacrylonitrile in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 799133
Summary Data
Genetic Toxicity Evaluation of Methacrylonitrile in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 926215
Summary Data