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TR-515: Propylene glycol mono-t-butyl ether (57018-52-7)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Male, Rats
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-515: Propylene glycol mono-t-butyl ether (57018-52-7).
Micronucleus - Mice
View
  • Male: Negative
    Female: Weakly Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TR-515: Propylene glycol mono-t-butyl ether (57018-52-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-515: Propylene glycol mono-t-butyl ether (57018-52-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. TR-515: Propylene glycol mono-t-butyl ether (57018-52-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-515 Toxicology and Carcinogenesis Studies of Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol Mono-t-Butyl Ether In Male NBR Rats (Inhalation Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in F344/N Rats via Whole Body Respiratory Exposure
2-Week Evaluation of the Toxicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in B6C3F1 Mice via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C90004) of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Propylene Glycol mono-t-Butyl Ether (57018-52-7) in Micronucleus Study A04540 in B6C3F1 Mice
Genetic Toxicity Evaluation of Propylene Glycol mono-t-Butyl Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A40505
Summary Data