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TR-535: 4-Methylimidazole (822-36-6)

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Equivocal Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-535: 4-Methylimidazole (822-36-6).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to TR-535: 4-Methylimidazole (822-36-6).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-535: 4-Methylimidazole (822-36-6).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information

NTP. TR-535: 4-Methylimidazole (822-36-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-535 Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity (C92013B) of 4-Methylimidazole (822-36-6) in F344/N Rats Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C92013B) of 4-Methylimidazole (822-36-6) in B6C3F1 Mice Exposed via Dosed Feed
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A12637 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A38684 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 4-Methylimidazole (822-36-6) in Micronucleus Study A49564 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 4-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A41578
Summary Data
Genetic Toxicity Evaluation of 4-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A53668
Summary Data