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TR-554: 5-(Hydroxymethyl)-2-furfural (67-47-0)


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Female, Rats
  • No Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
  • Some Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to TR-554: 5-(Hydroxymethyl)-2-furfural (67-47-0).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TR-554: 5-(Hydroxymethyl)-2-furfural (67-47-0).
Bacterial Mutagenicity
View
  • Weakly Positive
View
  • Negative

Citation Information


NTP. TR-554: 5-(Hydroxymethyl)-2-furfural (67-47-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-554 Toxicology and Carcinogenesis Studies of 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in F344/N Rats Exposed via Gavage
2-Week Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in B6C3F1 Mice Exposed via Gavage
3-Month Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C95011) of 5-(Hydroxymethyl)-2-Furfural (67-47-0) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C95011B) of 5-(Hydroxymethyl)-2-furfural (67-47-0) in F344/N Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C95011B) of 5-(Hydroxymethyl)-2-furfural (67-47-0) in B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 5-(Hydroxymethyl)-2-furfural (67-47-0) in Micronucleus Study A40470 in B6C3F1 Mice
Genetic Toxicity Evaluation of 5-(Hydroxymethyl)-2-furfural in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A22124
Summary Data
Genetic Toxicity Evaluation of 5-(Hydroxymethyl)-2-furfural in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A43477
Summary Data