TR-570: alpha/beta Thujone mixture (76231-76-0)
Publications
TR-570
Toxicology and Carcinogenesis Studies of ?,?-Thujone (CASRN 76231-76-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Study Data
Toxicity and Carcinogenicity Studies
2-Week Evaluation of the Toxicity (C99037) of alpha/beta Thujone Mixture (76231-76-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99037) of alpha/beta Thujone Mixture (76231-76-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P15 - Slide/Block Inventory
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99037) of alpha/beta Thujone Mixture (76231-76-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
2-Week Evaluation of the Toxicity (C99037) of alpha/beta Thujone Mixture (76231-76-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99037B) of alpha/beta Thujone Mixture (76231-76-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99037B) of alpha/beta Thujone Mixture (76231-76-0) in B6C3F1 Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99037B) of alpha/beta Thujone Mixture (76231-76-0) in F344/N Rats Exposed via Gavage
Study Tables
- E03 - Growth Curves (541 kB)
- E04 - Mean Body Weights and Survival Table (20 kB)
- E05 - Clinical Observations Summary (25 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (62 kB)
- P04 - Neoplasms by Individual Animal (699 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
- P08 - Statistical Analysis of Primary Tumors (232 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (902 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (543 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (574 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (64 kB)
- P40 - Survival Curves (566 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (310 kB)
- Female Individual Animal Clinical Observations (394 kB)
- Female Individual Animal Neoplastic Pathology Data (141 kB)
- Female Individual Animal Non Neoplastic Pathology Data (809 kB)
- Female Individual Animal Organ Weight Data (62 kB)
- Female Individual Animal Survival Data (33 kB)
- Male Individual Animal Body Weight Data (338 kB)
- Male Individual Animal Clinical Observations (523 kB)
- Male Individual Animal Neoplastic Pathology Data (314 kB)
- Male Individual Animal Non Neoplastic Pathology Data (956 kB)
- Male Individual Animal Organ Weight Data (62 kB)
- Male Individual Animal Survival Data (33 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C99037B) of alpha/beta Thujone Mixture (76231-76-0) in B6C3F1 Mice Exposed via Gavage
Study Tables
- E03 - Growth Curves (536 kB)
- E04 - Mean Body Weights and Survival Table (20 kB)
- E05 - Clinical Observations Summary (36 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (58 kB)
- P04 - Neoplasms by Individual Animal (811 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (51 kB)
- P08 - Statistical Analysis of Primary Tumors (219 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (938 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (460 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (723 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (60 kB)
- P40 - Survival Curves (551 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (381 kB)
- Female Individual Animal Clinical Observations (342 kB)
- Female Individual Animal Neoplastic Pathology Data (124 kB)
- Female Individual Animal Non Neoplastic Pathology Data (465 kB)
- Female Individual Animal Organ Weight Data (76 kB)
- Female Individual Animal Survival Data (41 kB)
- Male Individual Animal Body Weight Data (363 kB)
- Male Individual Animal Clinical Observations (144 kB)
- Male Individual Animal Neoplastic Pathology Data (164 kB)
- Male Individual Animal Non Neoplastic Pathology Data (481 kB)
- Male Individual Animal Organ Weight Data (76 kB)
- Male Individual Animal Survival Data (41 kB)
Special Evaluation of the Toxicity (C99037B) of alpha/beta Thujone Mixture (76231-76-0) in F344/N Rats Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E12 - Animal History
Individual Animal Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of alpha/beta Thujone Mixture (76231-76-0) in Micronucleus Study A26162 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of alpha/beta Thujone Mixture in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A36495
Summary Data
- G06 - Ames Summary Data (158 KB)