TR-574: Pyrogallol (87-66-1)
Study Results
Chronic Bioassay Level of Evidence
| Rats | |
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| Mice | |
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Genetic Toxicology
| Micronucleus - Mice |
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| Bacterial Mutagenicity |
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Publications
TR-574
Toxicology and Carcinogenesis Studies of Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1 Mice (Topical Application Studies)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C99032) of Pyrogallol (87-66-1) in F344/N Rats Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C99032) of Pyrogallol (87-66-1) in F344/N Rats Exposed via Topical Application
3-Month Evaluation of the Toxicity (C99032) of Pyrogallol (87-66-1) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P10 - Statistical Analysis Of Non-Neoplastic Lesions
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C99032) of Pyrogallol (87-66-1) in F344/N Rats Exposed via Topical Application
Study Tables
- E03 - Growth Curves (82 kB)
- E04 - Mean Body Weights and Survival Table (26 kB)
- E05 - Clinical Observations Summary (26 kB)
- E09 - Summary of Dermal Clinical Observations at Site of Application (16 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (63 kB)
- P04 - Neoplasms by Individual Animal (667 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
- P08 - Statistical Analysis of Primary Tumors (228 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (855 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (469 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (582 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (65 kB)
- P40 - Survival Curves (84 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (377 kB)
- Female Individual Animal Clinical Observations (497 kB)
- Female Individual Animal Neoplastic Pathology Data (161 kB)
- Female Individual Animal Non Neoplastic Pathology Data (668 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (382 kB)
- Male Individual Animal Clinical Observations (530 kB)
- Male Individual Animal Neoplastic Pathology Data (214 kB)
- Male Individual Animal Non Neoplastic Pathology Data (795 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C99032) of Pyrogallol (87-66-1) in B6C3F1 Mice Exposed via Topical Application
Study Tables
- E03 - Growth Curves (83 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (22 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (69 kB)
- P04 - Neoplasms by Individual Animal (791 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (49 kB)
- P08 - Statistical Analysis of Primary Tumors (236 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (653 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (613 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (72 kB)
- P40 - Survival Curves (83 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (386 kB)
- Female Individual Animal Clinical Observations (142 kB)
- Female Individual Animal Neoplastic Pathology Data (280 kB)
- Female Individual Animal Non Neoplastic Pathology Data (1 mB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (365 kB)
- Male Individual Animal Clinical Observations (175 kB)
- Male Individual Animal Neoplastic Pathology Data (202 kB)
- Male Individual Animal Non Neoplastic Pathology Data (1 mB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Pyrogallol (87-66-1) in Micronucleus Study A51963 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Pyrogallol (87-66-1) in Micronucleus Study A76126 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Pyrogallol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A22702
Summary Data
- G06 - Ames Summary Data (63 KB)
Genetic Toxicity Evaluation of Pyrogallol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A98424
Summary Data
- G06 - Ames Summary Data (80 KB)