TR-586: CIMSTAR 3800 (CIMSTAR3800)
Study Results
Chronic Bioassay Level of Evidence
| Rats | |
|---|---|
View
|
|
| Mice | |
|---|---|
View
|
|
Genetic Toxicology
| Micronucleus - Mice |
|---|
View
|
| Micronucleus - Rats |
|---|
View
|
| Bacterial Mutagenicity |
|---|
View
|
Publications
TR-586
Toxicology and Carcinogenesis Studies of CIMSTAR® 3800 (CASRN CIMSTAR3800) in Wistar Han Rats and B6C3F1 Mice (Inhalation Studies)
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in F344/NTac Rats via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (83 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (21 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (24 kB)
- P04 - Neoplasms by Individual Animal (123 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (151 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (85 kB)
- P14 - Individual Animal Pathology Data (284 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (25 kB)
- P40 - Survival Curves (76 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (37 kB)
- Female Individual Animal Clinical Observations (31 kB)
- Female Individual Animal Non Neoplastic Pathology Data (164 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (37 kB)
- Male Individual Animal Clinical Observations (23 kB)
- Male Individual Animal Non Neoplastic Pathology Data (168 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
3-Month Evaluation of the Toxicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (87 kB)
- E04 - Mean Body Weights and Survival Table (15 kB)
- E05 - Clinical Observations Summary (21 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (23 kB)
- P04 - Neoplasms by Individual Animal (119 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (23 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (142 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (64 kB)
- P14 - Individual Animal Pathology Data (274 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (24 kB)
- P40 - Survival Curves (76 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (36 kB)
- Female Individual Animal Clinical Observations (17 kB)
- Female Individual Animal Non Neoplastic Pathology Data (95 kB)
- Female Individual Animal Organ Weight Data (19 kB)
- Female Individual Animal Survival Data (11 kB)
- Male Individual Animal Body Weight Data (36 kB)
- Male Individual Animal Clinical Observations (39 kB)
- Male Individual Animal Non Neoplastic Pathology Data (91 kB)
- Male Individual Animal Organ Weight Data (19 kB)
- Male Individual Animal Survival Data (11 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Wistar Han Rats via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (67 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (25 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (52 kB)
- P04 - Neoplasms by Individual Animal (665 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (48 kB)
- P08 - Statistical Analysis of Primary Tumors (284 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (784 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (327 kB)
- P11 - Statistical Analysis of Survival Data (24 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (616 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (54 kB)
- P40 - Survival Curves (64 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (358 kB)
- Female Individual Animal Clinical Observations (154 kB)
- Female Individual Animal Neoplastic Pathology Data (105 kB)
- Female Individual Animal Non Neoplastic Pathology Data (634 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (362 kB)
- Male Individual Animal Clinical Observations (153 kB)
- Male Individual Animal Neoplastic Pathology Data (93 kB)
- Male Individual Animal Non Neoplastic Pathology Data (723 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20515) of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in B6C3F1 Mice via Whole Body Respiratory Exposure
Study Tables
- E03 - Growth Curves (64 kB)
- E04 - Mean Body Weights and Survival Table (24 kB)
- E05 - Clinical Observations Summary (20 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (62 kB)
- P04 - Neoplasms by Individual Animal (728 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (52 kB)
- P08 - Statistical Analysis of Primary Tumors (204 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (885 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (375 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (647 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (64 kB)
- P40 - Survival Curves (63 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (372 kB)
- Female Individual Animal Clinical Observations (62 kB)
- Female Individual Animal Neoplastic Pathology Data (242 kB)
- Female Individual Animal Non Neoplastic Pathology Data (647 kB)
- Female Individual Animal Organ Weight Data (57 kB)
- Female Individual Animal Survival Data (34 kB)
- Male Individual Animal Body Weight Data (345 kB)
- Male Individual Animal Clinical Observations (73 kB)
- Male Individual Animal Neoplastic Pathology Data (132 kB)
- Male Individual Animal Non Neoplastic Pathology Data (624 kB)
- Male Individual Animal Organ Weight Data (57 kB)
- Male Individual Animal Survival Data (34 kB)
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F06575 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 (CIMSTAR3800) in Micronucleus Study F64536 in F344/NTac Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Metal Working Fluids: CIMSTAR 3800 in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A69652
Summary Data
- G06 - Ames Summary Data (76 KB)