TR-605: Sulfolane (126-33-0)
Publications
TR-605
NTP Technical Report on the Toxicology and Carcinogenesis Studies of Sulfolane (CASRN 126-33-0) Administered in Drinking Water to Sprague Dawley (Hsd:Sprague Dawley SD) Rats and B6C3F1/N Mice
Study Data
Toxicity and Carcinogenicity Studies
2-Year (with Three-Month Interim) Evaluation of the Toxicity (C11054B-02) of Sulfolane (126-33-0) in B6C3F1/N Mice Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (126 kB)
- I02 - Animal Removals (2 mB)
- I03 - Growth Curve (2 mB)
- I03C - Growth Curve (2 mB)
- I04 - Mean Body Weight Summary (833 kB)
- I04G - Mean Body Weight Gain (211 kB)
- I05 - Clinical Observations Summary (973 kB)
- I07 - Mean Water Consumption (435 kB)
- I08 - Mean Test Compound Consumption (732 kB)
- PA02 - Neoplastic Lesion Summary with Percent Incidence (266 kB)
- PA03 - Nonneoplastic Lesion Summary with Percent Incidence (1 mB)
- PA05 - Incidence Rates of Neoplastic Lesions with Systemic Lesions Abridged (1 mB)
- PA06 - Organ Weights Summary (180 kB)
- PA08 - Statistical Analysis of Neoplastic Lesions (3 mB)
- PA08X - Statistical Analysis of Neoplastic Lesions (282 kB)
- PA10 - Statistical Analysis of Nonneoplastic Lesions (3 mB)
- PA10X - Statistical Analysis of Nonneoplastic Lesions (291 kB)
- PA11 - Statistical Analysis of Survival Data (284 kB)
- PA14 - Individual Animal Pathology Data (35 mB)
- PA18 - Incidenc Rates of Nonneoplastic Lesions by Anatomic Site with Average Severity Grade (265 kB)
- PA40 - Suvival Curve (519 kB)
- PA43 - Hematology Summary (343 kB)
- PA46 - Summary of Gross Pathology (1 mB)
- PA48 - Summary of Tissue Concentration (85 kB)
- Vaginal Cytology Markov Model (200 kB)
- Vaginal Cytology Plots (145 kB)
- Vaginal Cytology Summary (125 kB)
Individual Animal Data
- Individual Animal Body Weight Data (584 kB)
- Individual Animal Clinical Observations Data (624 kB)
- Individual Animal Consumption Data (962 kB)
- Individual Animal Gross Pathology Data (2 mB)
- Individual Animal Hematology Data (16 kB)
- Individual Animal Histopathology Data (1 mB)
- Individual Animal Organ Weight Data (14 kB)
- Individual Animal Removal Reasons Data (30 kB)
- Individual Animal Tissue Concentration Data (7 kB)
Perinatal and Two-year (Three-month Interim) (C11054B-01) in Harlan Sprague Dawley Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (120 kB)
- I02 - Animal Removals (644 kB)
- I03 - Growth Curve (3 mB)
- I03C - Growth Curve (3 mB)
- I04 - Mean Body Weight Summary (342 kB)
- I04G - Mean Body Weight Gain (225 kB)
- I05 - Clinical Observations Summary (124 kB)
- I05D - Detailed Clinical Observations Summary (104 kB)
- I05P - Pup Clinical Observations Summary (746 kB)
- I05PD - Pup Detailed Clinical Observations Summary (598 kB)
- I07 - Mean Water Consumption (247 kB)
- I08 - Mean Test Compound Consumption (165 kB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (570 kB)
- PA03R - Nonneoplastic Lesion Summary with Percent and Litter Incidence (703 kB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (792 kB)
- PA06 - Organ Weights Summary (76 kB)
- PA08R - Statistical Analysis of Neoplastic Lesions with Litter Incidence (519 kB)
- PA10R - Statistical Analysis of Nonneoplastic Lesions with Litter Incidence (549 kB)
- PA14 - Individual Animal Pathology Data (8 mB)
- PA18R - Nonneoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (187 kB)
- PA41 - Clinical Chemistry Summary (93 kB)
- PA43 - Hematology Summary (100 kB)
- PA46 - Summary of Gross Pathology (502 kB)
- PA48 - Summary of Tissue Concentration (286 kB)
- R01 - Multigeneration Cross Reference (783 kB)
- R02 - Reproductive Performance Summary (179 kB)
- R03 - Summary of Litter Data (127 kB)
- R04 - Anogenital Distance Summary (253 kB)
- R16 - Pubertal Markers Summary (399 kB)
- R19 - Pup Mean Body Weight Summary (614 kB)
- R19C - Pup Growth Curve (1 mB)
- R19G - Pup Mean Body Weight Gain (573 kB)
- Vaginal Cytology Markov Model (180 kB)
- Vaginal Cytology Plots (145 kB)
- Vaginal Cytology Summary (125 kB)
Individual Animal Data
- Individual Animal Body Weight Data (553 kB)
- Individual Animal Clinical Chemistry Data (14 kB)
- Individual Animal Clinical Observations Data (525 kB)
- Individual Animal Consumption Data (841 kB)
- Individual Animal Developmental Markers Data (191 kB)
- Individual Animal Gross Pathology Data (209 kB)
- Individual Animal Hematology Data (17 kB)
- Individual Animal Histopathology Data (87 kB)
- Individual Animal Litter Data (250 kB)
- Individual Animal Organ Weight Data (15 kB)
- Individual Animal Pup Body Weight Data (462 kB)
- Individual Animal Pup Clinical Observations Data (565 kB)
- Individual Animal Removal Reasons Data (54 kB)
- Individual Animal Reproductive Performance Data (13 kB)
- Individual Animal Tissue Concentration Data (7 kB)
Perinatal and Two-year (C11054B-01) study in Harlan Sprague Dawley Exposed via Dosed Water
Study Tables
- I01 - Animal Removal Summary (286 kB)
- I02 - Animal Removals (7 mB)
- I03 - Growth Curve (1 mB)
- I03C - Growth Curve (1 mB)
- I04 - Mean Body Weight Summary (679 kB)
- I04G - Mean Body Weight Gain (294 kB)
- I05 - Clinical Observations Summary (4 mB)
- I07 - Mean Water Consumption (651 kB)
- I08 - Mean Test Compound Consumption (444 kB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (2 mB)
- PA03R - Nonneoplastic Lesion Summary with Percent and Litter Incidence (2 mB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (1 mB)
- PA08L - Statistical Analysis of Neoplastic Lesions with Litter Incidence (6 mB)
- PA10L - Statistical Analysis of Nonneoplastic Lesions with Litter Incidence (9 mB)
- PA11 - Statistical Analysis of Survival Data (690 kB)
- PA14 - Individual Animal Pathology Data (7 mB)
- PA18R - Nonneoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (2 mB)
- PA40 - Survival Curve (754 kB)
- PA46 - Summary of Gross Pathology (3 mB)
Individual Animal Data
- Individual Animal Body Weight Data (364 kB)
- Individual Animal Clinical Observations Data (423 kB)
- Individual Animal Consumption Data (526 kB)
- Individual Animal DamID and PupID Data (22 kB)
- Individual Animal Gross Pathology Data (1 mB)
- Individual Animal Histopathology Data (1 mB)
- Individual Animal Removal Reasons Data (27 kB)