U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

4-Chloronitrobenzene (100-00-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5020281

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Chloronitrobenzene (100-00-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to 4-Chloronitrobenzene (100-00-5).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Chloronitrobenzene (100-00-5).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive

Citation Information

NTP. 4-Chloronitrobenzene (100-00-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TOX-33 Toxicity Studies of 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene (CASRN 100-00-5) Administered by Inhalation to F344/N Rats and B6C3F1Mice
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Zimmering, S., Mason, J.M., Valencia, R., and Woodruff, R.C. Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 87-100
Zimmering, S., Mason, J.M., and Valencia, R. Chemical mutagenesis testing in Drosophila. VII. Results of 22 coded compounds tested in larval feeding experiments. Environ. Molec. Mutagen. Vol. 14 (1989) 245-252
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data

Protocol

Toxicity and Carcinogenicity Studies

3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in F344 Rats via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
Clinical Chemistry Reports
3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in B6C3F1 Mice via Whole Body Respiratory Exposure. NTP Special Study
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in F344/N Rats via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in B6C3F1 Mice via Whole Body Respiratory Exposure
Pathology Tables
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of 4-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 300619
Summary Data
Genetic Toxicity Evaluation of 4-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 975957
Summary Data

Other NTP Studies

ADME/TK Evaluation (S0077) of 4-Chloronitrobenzene (100-00-5) in F344 Rats Exposed via Topical Application
Data Summary
ADME/TK Evaluation (S0105) of 4-Chloronitrobenzene (100-00-5) in F344 Rats Exposed via Gavage
Data Summary
ADME/TK Evaluation (S0363) of 4-Chloronitrobenzene (100-00-5) in F344 Rats Exposed via Gavage
Data Summary
ADME/TK Evaluation (S0779) of 4-Chloronitrobenzene (100-00-5) in F344 Rats Exposed via Gavage
Data Summary

NTP Data Collections