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TOX-33: 2-Chloronitrobenzene (88-73-3), 4-Chloronitrobenzene (100-00-5)


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to TOX-33: 2-Chloronitrobenzene (88-73-3), 4-Chloronitrobenzene (100-00-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to TOX-33: 2-Chloronitrobenzene (88-73-3), 4-Chloronitrobenzene (100-00-5).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to TOX-33: 2-Chloronitrobenzene (88-73-3), 4-Chloronitrobenzene (100-00-5).
Bacterial Mutagenicity
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  • Positive
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  • Weakly Positive
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  • Positive
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  • Positive
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  • Positive
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  • Positive
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  • Positive

Citation Information


NTP. TOX-33: 2-Chloronitrobenzene (88-73-3), 4-Chloronitrobenzene (100-00-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-33 Toxicity Studies of 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene (CASRN 100-00-5) Administered by Inhalation to F344/N Rats and B6C3F1Mice

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C62248) of 2-Chloronitrobenzene (88-73-3) in B6C3F1 Mice via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C62259) of 4-Chloronitrobenzene (100-00-5) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 123419
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 217675
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 270911
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 334206
Summary Data
Genetic Toxicity Evaluation of 2-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 689524
Summary Data
Genetic Toxicity Evaluation of 4-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 300619
Summary Data
Genetic Toxicity Evaluation of 4-Chloronitrobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 975957
Summary Data